At stalled replication forks, the E3 ubiquitin ligase HLTF interacts with PCNA monoubiquitinated at lysine-164 (monoUb-K164-PCNA), the RAD18:UBE2B complex (RAD18:RAD6 complex), and the Ub:UBE2N:UBE2V2 complex (UBC13:MMS2 complex with ubiquitin conjugated to UBC13) (Unk et al. 2008, Motegi et al. 2008, MacKay et al. 2009).
MacKay, C, Toth, R, Rouse, J
Motegi, A, Liaw, HJ, Lee, KY, Roest, HP, Maas, A, Wu, X, Moinova, H, Markowitz, SD, Ding, H, Hoeijmakers, JH, Myung, K
Unk, I, Hajdu, I, Fatyol, K, Hurwitz, J, Yoon, JH, Prakash, L, Prakash, S, Haracska, L
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