Peroxynitrite and carbon dioxide react to nitrosoperoxycarbonate

Stable Identifier
R-HSA-8942075
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
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Peroxynitrite and carbon dioxide react to nitrosoperoxycarbonate
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Peroxynitrite anion rapidly reacts with carbon dioxide to yield a reactive adduct, nitrosoperoxycarbonate anion (ONOOCOO-), which can participate in oxidation and nitration processes, thus redirecting the primary reactivity of peroxynitrite (Denicola A et al. 1996).

Literature References
PubMed ID Title Journal Year
8806753 Peroxynitrite reaction with carbon dioxide/bicarbonate: kinetics and influence on peroxynitrite-mediated oxidations

Denicola, A, Freeman, BA, Trujillo, M, Radi, R

Arch. Biochem. Biophys. 1996
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Participant Of
hasEvent
Authored
Shamovsky, V  (2018-10-23)
Reviewed
Nüsse, O  (2018-11-07)
Created
Shamovsky, V  (2016-10-08)