Reactome | CDKN1C [cytosol]

CDKN1C [cytosol]

Stable Identifier

R-HSA-8941913

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Cyclin-dependent kinase inhibitor 1C, p57Kip2, Cyclin-dependent kinase inhibitor p57, KIP2, CDN1C_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P49918 CDKN1C

Gene Names

CDKN1C, KIP2

Chain

chain:1-316

Reference Genes

BioGPS Gene:1028 CDKN1C

COSMIC (genes):CDKN1C CDKN1C

CTD Gene:1028 CDKN1C

dbSNP Gene:1028 CDKN1C

ENSEMBL:ENSG00000129757 CDKN1C

HGNC:1786 CDKN1C

KEGG:hsa:1028 CDKN1C

Monarch:1028 CDKN1C

NCBI Gene:1028 CDKN1C

OMIM:600856 CDKN1C

UCSC:P49918 CDKN1C

Reference Transcript

Participates

as a candidate of

CDKN1A,CDKN1B,(CDKN1C) [cytosol] (Homo sapiens)

Other forms of this molecule

p-Y91-CDKN1C [cytosol]

CDKN1C [nucleoplasm]

Inferred To

dap [cytosol] (Drosophila melanogaster)

cdknx [cytosol] (Xenopus tropicalis)

CDKN1C [cytosol] (Bos taurus)

CDKN1C [cytosol] (Canis familiaris)

CDKN1C [cytosol] (Sus scrofa)

cdkn1ca [cytosol] (Danio rerio)

Cdkn1c [cytosol] (Mus musculus)

Cdkn1c [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_000067.1, NP_001116103.1, NP_001116102.1, XP_016872577.1

ENSEMBL

ENSG00000129757, ENST00000440480, ENSP00000413720, ENSP00000411257, ENSP00000411552, ENST00000414822, ENST00000430149

OpenTargets

ENSG00000129757

GeneCards

CDKN1C

HPA

ENSG00000129757-CDKN1C

PRO

P49918

Pharos - Targets

P49918

Orphanet

CDKN1C

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P24941 CDK2	5	p-T160-CDK2 [nucleoplasm] (R-HSA-187967) CDK2 [nucleoplasm] (R-HSA-68365) CDK2 [cytosol] (R-HSA-157440) p-CDK2 [nucleoplasm] (R-HSA-68370) p-Y15-CDK2 [nucleoplasm] (R-HSA-187905)	0.643	5
UniProt:P11802 CDK4	3	p-T172-CDK4 [nucleoplasm] (R-HSA-113830) CDK4 [nucleoplasm] (R-HSA-113843) CDK4 [cytosol] (R-HSA-68330)	0.564	2
UniProt:P33993 MCM7	1	MCM7 [nucleoplasm] (R-HSA-68555)	0.527	2
UniProt:P30281 CCND3	2	CCND3 [nucleoplasm] (R-HSA-113835) CCND3 [cytosol] (R-HSA-68333)	0.527	3
UniProt:P24385 CCND1	4	CCND1 [nucleoplasm] (R-HSA-113832) CCND1 [cytosol] (R-HSA-68328) p-T286-CCND1 [cytosol] (R-HSA-75813) p-T286-CCND1 [nucleoplasm] (R-HSA-75811)	0.527	3

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