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LRRC8E [plasma membrane]
Stable Identifier
R-HSA-8941539
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Volume-regulated anion channel subunit LRRC8E, LRC8E_HUMAN
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
Miscellaneous transport and binding events (Homo sapiens)
VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Homo sapiens)
VRAC heteromer [plasma membrane] (Homo sapiens)
LRRC8A:LRRC8E [plasma membrane] (Homo sapiens)
LRRC8E [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6NSJ5 LRRC8E
Gene Names
LRRC8E
Chain
chain:1-796
Reference Genes
BioGPS Gene:80131 LRRC8E
COSMIC (genes):LRRC8E LRRC8E
CTD Gene:80131 LRRC8E
dbSNP Gene:80131 LRRC8E
ENSEMBL:ENSG00000171017 LRRC8E
ENSEMBL_homo_sapiens_GENE:ENSG00000171017.11 LRRC8E
HGNC:26272 LRRC8E
KEGG Gene (Homo sapiens):80131 LRRC8E
Monarch:80131 LRRC8E
NCBI Gene:80131 LRRC8E
OMIM:612891 LRRC8E
UCSC:Q6NSJ5 LRRC8E
Reference Transcript
RefSeq:NM_001268285.2 LRRC8E
RefSeq:NM_025061.5 LRRC8E
RefSeq:NM_001268284.2 LRRC8E
RefSeq:XM_011528319.2 LRRC8E
Other Identifiers
11727264_at
16857794
220174_PM_at
220174_at
239433_PM_at
239433_at
3819249
3819250
3819253
3819254
3819255
3819256
3819257
3819258
3819259
55744_at
80131
8025347
A_14_P101979
A_23_P90032
A_24_P348203
GE83066
GO:0005215
GO:0005225
GO:0005515
GO:0005737
GO:0005764
GO:0005765
GO:0005773
GO:0005783
GO:0005789
GO:0005886
GO:0006811
GO:0006884
GO:0007165
GO:0015810
GO:0016020
GO:0023052
GO:0034220
GO:0034702
GO:0043226
GO:0055085
GO:0071470
GO:0098656
GO:0140361
HMNXSV003058078
Hs.105822.0.A1_3p_at
ILMN_1669052
ILMN_2048633
PH_hs_0034155
TC19000139.hg
g13376596_3p_at
Participates
as a component of
LRRC8A:LRRC8E [plasma membrane] (Homo sapiens)
Inferred To
soc-2 [plasma membrane]
(Caenorhabditis elegans)
LRRC8E [plasma membrane]
(Bos taurus)
LRRC8E [plasma membrane]
(Canis familiaris)
Lrrc8e [plasma membrane]
(Mus musculus)
Lrrc8e [plasma membrane]
(Rattus norvegicus)
Sur-8 [plasma membrane]
(Drosophila melanogaster)
si:zfos-323e3.4 [plasma membrane]
(Danio rerio)
Cross References
RefSeq
NP_001255213.1
,
NP_001255214.1
,
XP_011526621.1
,
NP_079337.2
OpenTargets
ENSG00000171017
HPA
ENSG00000171017-LRRC8E
GeneCards
Q6NSJ5
Ensembl
ENSG00000171017
,
ENST00000306708
,
ENSP00000306524
,
ENST00000618098
,
ENSP00000479953
PRO
Q6NSJ5
Pharos - Targets
Q6NSJ5
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P11532 DMD
1
DMD [cytosol]
(R-HSA-390567)
0.527
2
UniProt:P43119 PTGIR
1
PTGIR [plasma membrane]
(R-HSA-391834)
0.527
2
UniProt:Q9GZQ4 NMUR2
1
NMUR2 [plasma membrane]
(R-HSA-964816)
0.527
2
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