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LRRC8B [plasma membrane]
Stable Identifier
R-HSA-8941535
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Volume-regulated anion channel subunit LRRC8B, LRC8B_HUMAN
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
Miscellaneous transport and binding events (Homo sapiens)
VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Homo sapiens)
VRAC heteromer [plasma membrane] (Homo sapiens)
LRRC8A:LRRC8B [plasma membrane] (Homo sapiens)
LRRC8B [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6P9F7 LRRC8B
Gene Names
LRRC8B, KIAA0231, UNQ6413/PRO21207
Chain
chain:1-803
Reference Genes
BioGPS Gene:23507 LRRC8B
COSMIC (genes):LRRC8B LRRC8B
CTD Gene:23507 LRRC8B
dbSNP Gene:23507 LRRC8B
ENSEMBL:ENSG00000197147 LRRC8B
HGNC:30692 LRRC8B
KEGG:hsa:23507 LRRC8B
Monarch:23507 LRRC8B
NCBI Gene:23507 LRRC8B
OMIM:612888 LRRC8B
UCSC:Q6P9F7 LRRC8B
Reference Transcript
RefSeq:XM_005270701.4 LRRC8B
RefSeq:XM_017000884.1 LRRC8B
RefSeq:NM_015350.2 LRRC8B
RefSeq:XM_017000883.1 LRRC8B
RefSeq:XM_005270703.4 LRRC8B
RefSeq:XM_011541145.2 LRRC8B
RefSeq:NM_001134476.1 LRRC8B
RefSeq:XM_011541146.2 LRRC8B
RefSeq:XM_017000885.1 LRRC8B
RefSeq:XM_011541144.2 LRRC8B
RefSeq:XM_011541143.2 LRRC8B
RefSeq:XM_005270702.4 LRRC8B
Other Identifiers
11732413_a_at
11732414_a_at
11745063_x_at
16666965
212976_PM_at
212976_at
212978_PM_at
212978_at
2345882
2345883
2345884
2345886
2345896
2345897
2345899
2345900
2345901
2345903
2345905
2345906
2345907
2345914
2345915
2345916
2345917
2345918
23507
2974303
2974306
33771_at
7902861
A_14_P135229
A_23_P115167
A_24_P345131
A_24_P943949
D86984_at
GE62409
GO:0005215
GO:0005225
GO:0005515
GO:0005737
GO:0005783
GO:0005789
GO:0005886
GO:0015810
GO:0016020
GO:0034220
GO:0034702
GO:0043226
GO:0055085
GO:0098656
GO:0140361
HMNXSV003001771
Hs.199243.0.S1_3p_at
Hs.199243.0.S2_3p_at
ILMN_1712128
ILMN_1838313
PH_hs_0024440
PH_hs_0037351
TC01000837.hg
Participates
as a component of
LRRC8A:LRRC8B [plasma membrane] (Homo sapiens)
Inferred To
soc-2 [plasma membrane]
(Caenorhabditis elegans)
Homologues of LRRC8B [plasma membrane]
(Danio rerio)
LRRC8B [plasma membrane]
(Bos taurus)
LRRC8B [plasma membrane]
(Sus scrofa)
Sur-8 [plasma membrane]
(Drosophila melanogaster)
lrrc8ab [plasma membrane]
(Danio rerio)
Lrrc8b [plasma membrane]
(Mus musculus)
Lrrc8b [plasma membrane]
(Rattus norvegicus)
LOC107056693 [plasma membrane]
(Gallus gallus)
lrrc8aa [plasma membrane]
(Danio rerio)
Cross References
ENSEMBL
ENST00000640258
,
ENSP00000492151
,
ENST00000639264
,
ENSP00000332674
,
ENSP00000491377
,
ENST00000330947
,
ENSG00000197147
OpenTargets
ENSG00000197147
GeneCards
LRRC8B
HPA
ENSG00000197147-LRRC8B
PRO
Q6P9F7
Pharos - Targets
Q6P9F7
GlyGen
Q6P9F7
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O43808 SLC25A17
2
SLC25A17 [cytosol]
(R-HSA-9603781)
SLC25A17 [peroxisomal membrane]
(R-HSA-389642)
0.527
2
UniProt:Q13370 PDE3B
2
p-S295-PDE3B [cytosol]
(R-HSA-162419)
PDE3B [cytosol]
(R-HSA-162348)
0.527
2
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