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LRRC8C [plasma membrane]
Stable Identifier
R-HSA-8941519
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Volume-regulated anion channel subunit LRRC8C, LRC8C_HUMAN
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
Miscellaneous transport and binding events (Homo sapiens)
VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Homo sapiens)
VRAC heteromer [plasma membrane] (Homo sapiens)
LRRC8A:LRRC8C [plasma membrane] (Homo sapiens)
LRRC8C [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8TDW0 LRRC8C
Gene Names
LRRC8C, AD158, FAD158
Chain
chain:1-803
Reference Genes
BioGPS Gene:84230 LRRC8C
COSMIC (genes):LRRC8C LRRC8C
CTD Gene:84230 LRRC8C
dbSNP Gene:84230 LRRC8C
ENSEMBL:ENSG00000171488 LRRC8C
HGNC:25075 LRRC8C
KEGG:hsa:84230 LRRC8C
Monarch:84230 LRRC8C
NCBI Gene:84230 LRRC8C
OMIM:612889 LRRC8C
UCSC:Q8TDW0 LRRC8C
Reference Transcript
RefSeq:NM_032270.4 LRRC8C
RefSeq:XM_011542282.2 LRRC8C
RefSeq:XM_017002503.1 LRRC8C
Other Identifiers
11723591_at
11723592_at
11761815_at
1558517_3p_s_at
1558517_PM_s_at
1558517_s_at
1562712_PM_at
1562712_at
1570007_PM_at
1570007_at
223533_PM_at
223533_at
228314_PM_at
228314_at
2345930
2345931
2345936
2345946
2345949
2345952
2345953
2345954
2345955
2345956
2345957
2345958
2345974
2345977
2345978
2345979
2345980
2345981
2345982
2345984
50007_at
55997_at
63157_at
7902874
84230
86568_at
A_14_P123145
A_21_P0001336
A_23_P103775
A_33_P3406030
GE62773
GE738065
GE907166
GO:0005215
GO:0005225
GO:0005515
GO:0005730
GO:0005737
GO:0005783
GO:0005789
GO:0005886
GO:0006396
GO:0015734
GO:0015810
GO:0016020
GO:0030154
GO:0034214
GO:0034220
GO:0034702
GO:0043226
GO:0045444
GO:0055085
GO:0065003
GO:0071470
GO:0098656
GO:0140361
HMNXSV003012931
HMNXSV003031252
HMNXSV003032592
HMNXSV003035377
Hs.24181.0.A1_3p_at
Hs2.24181.1.S1_3p_at
Hs2.24181.1.S1_3p_s_at
Hs2.385539.1.S1_3p_at
Hs2.438434.1.S1_3p_at
ILMN_1900471
ILMN_2094396
PH_hs_0002135
PH_hs_0024916
TC01000839.hg
TC01004522.hg
TC01004523.hg
g12053332_3p_at
p17732
Participates
as a component of
LRRC8A:LRRC8C [plasma membrane] (Homo sapiens)
Inferred To
soc-2 [plasma membrane]
(Caenorhabditis elegans)
Lrrc8c [plasma membrane]
(Mus musculus)
Lrrc8c [plasma membrane]
(Rattus norvegicus)
Sur-8 [plasma membrane]
(Drosophila melanogaster)
LRRC8C [plasma membrane]
(Bos taurus)
LRRC8C [plasma membrane]
(Canis familiaris)
LRRC8C [plasma membrane]
(Gallus gallus)
Cross References
ENSEMBL
ENSG00000171488
,
ENST00000370454
,
ENSP00000359483
OpenTargets
ENSG00000171488
GeneCards
LRRC8C
HPA
ENSG00000171488-LRRC8C
PRO
Q8TDW0
Pharos - Targets
Q8TDW0
PDB
8DXP
,
8DXR
,
8DXQ
,
8DXO
,
8DXN
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P25090 FPR2
4
FPR2 [plasma membrane]
(R-HSA-416408)
FPR2 [tertiary granule membrane]
(R-HSA-6803296)
FPR2 [specific granule membrane]
(R-HSA-6803319)
FPR2 [ficolin-1-rich granule membrane]
(R-HSA-6803335)
0.527
2
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