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GPI-LSAMP [plasma membrane]
Stable Identifier
R-HSA-8940809
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Limbic system-associated membrane protein precursor, LAMP_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Post-translational modification: synthesis of GPI-anchored proteins (Homo sapiens)
GPLD1 hydrolyses GPI-anchors from proteins (Homo sapiens)
GPI-anchored proteins [plasma membrane] (Homo sapiens)
GPI-LSAMP [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13449 LSAMP
Gene Names
LSAMP, IGLON3, LAMP
Chain
signal peptide:1-28, chain:29-315, propeptide:316-338
Reference Genes
BioGPS Gene:4045 LSAMP
COSMIC (genes):LSAMP LSAMP
CTD Gene:4045 LSAMP
dbSNP Gene:4045 LSAMP
ENSEMBL:ENSG00000185565 LSAMP
HGNC:6705 LSAMP
Monarch:4045 LSAMP
NCBI Gene:4045 LSAMP
OMIM:603241 LSAMP
UCSC:Q13449 LSAMP
Reference Transcript
RefSeq:NM_001318915.1 LSAMP
RefSeq:NM_002338.4 LSAMP
Other Identifiers
11726502_a_at
11760699_a_at
11760700_at
11760701_x_at
16957675
17123456
214460_PM_at
214460_at
228218_PM_at
228218_at
229244_PM_at
229244_at
235111_PM_at
235111_at
235494_PM_at
235494_at
2688743
2690017
2690018
2690019
2690020
2690021
2690022
2690023
2690024
2690025
2690026
2690027
2690029
2690030
2690031
2690036
2690037
2690038
2690039
2690041
2690042
2690049
2690050
2690053
2690059
2690135
2690136
2690137
2690176
2690178
2690183
2690184
2690551
2690596
2690597
2816289
3020269
36256_at
4045
42982_at
42983_at
43930_at
52678_at
58589_s_at
61321_f_at
69173_at
8089714
81247_at
91814_s_at
A_23_P301855
A_24_P794631
A_32_P92445
GE477339
GE59153
GO:0005515
GO:0005576
GO:0005829
GO:0005886
GO:0007155
GO:0007399
GO:0016020
GO:0048856
GO:0098552
HMNXSV003007775
HMNXSV003037784
Hs.25231.0.A1_3p_at
Hs.26409.0.S1_3p_at
Hs.26479.0.A1_3p_at
Hs.288405.0.A1_3p_at
Hs.288405.1.A1_3p_at
ILMN_1739154
ILMN_1907728
PH_hs_0028325
TC03001673.hg
TC03003040.hg
TC03003041.hg
Participates
as a member of
GPI-anchored proteins [plasma membrane] (Homo sapiens)
Other forms of this molecule
cleaved GPI-LSAMP [extracellular region]
Inferred To
Ama [plasma membrane]
(Drosophila melanogaster)
LSAMP [plasma membrane]
(Bos taurus)
LSAMP [plasma membrane]
(Canis familiaris)
LSAMP [plasma membrane]
(Sus scrofa)
Lsamp [plasma membrane]
(Mus musculus)
Lsamp [plasma membrane]
(Rattus norvegicus)
GPI-LSAMP [plasma membrane]
(Gallus gallus)
Modified Residues
Name
L-asparagine amide (GPI-anchor amidated amino acid carboxyl end residue(1−)) at 315
Coordinate
315
Modification
GPI-anchor amidated amino acid carboxyl end residue(1−)
PsiMod Name
L-asparagine amide
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to L-asparagine amide.
Cross References
ENSEMBL
ENST00000490035
,
ENSP00000419000
OpenTargets
ENSG00000185565
HPA
ENSG00000185565-LSAMP
PRO
Q13449
Pharos - Targets
Q13449
GlyGen
Q13449
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q14154 DELE1
3
DELE1 [mitochondrial inner membrane]
(R-HSA-9840377)
DELE1(143-515) [cytosol]
(R-HSA-9840380)
DELE1(143-515) [mitochondrial inner membrane]
(R-HSA-9840386)
0.556
3
UniProt:Q13352 ITGB3BP
2
ITGB3BP [nucleoplasm]
(R-HSA-606325)
ITGB3BP [cytosol]
(R-HSA-3006405)
0.556
3
UniProt:Q14457 BECN1
4
BECN1 [cytosol]
(R-HSA-1632841)
p-S15-BECN1 [cytosol]
(R-HSA-5682391)
ISG15-K-BECN1 [cytosol]
(R-HSA-9853030)
K63polyUb-BECN1 [cytosol]
(R-HSA-6782989)
0.556
3
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
0.527
4
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