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GPI-RTN4RL2 [plasma membrane]
Stable Identifier
R-HSA-8940807
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Reticulon-4 receptor-like 2, R4RL2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Post-translational modification: synthesis of GPI-anchored proteins (Homo sapiens)
GPLD1 hydrolyses GPI-anchors from proteins (Homo sapiens)
GPI-anchored proteins [plasma membrane] (Homo sapiens)
GPI-RTN4RL2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86UN3 RTN4RL2
Gene Names
RTN4RL2, NGRH1, NGRL3
Chain
signal peptide:1-46, chain:47-390, propeptide:391-420
Reference Genes
BioGPS Gene:349667 RTN4RL2
COSMIC (genes):RTN4RL2 RTN4RL2
CTD Gene:349667 RTN4RL2
dbSNP Gene:349667 RTN4RL2
ENSEMBL:ENSG00000186907 RTN4RL2
HGNC:23053 RTN4RL2
KEGG:hsa:349667 RTN4RL2
Monarch:349667 RTN4RL2
NCBI Gene:349667 RTN4RL2
OMIM:610462 RTN4RL2
UCSC:Q86UN3 RTN4RL2
Reference Transcript
RefSeq:NM_178570.3 RTN4RL2
Other Identifiers
11743023_at
16724840
229345_PM_at
229345_at
3331275
3331276
3331284
3331285
3331286
3331291
3331292
3331293
3331294
3331295
3331296
3331297
3331298
3331299
349667
7940022
83228_at
86384_at
ADDON002598.hg
A_23_P139104
A_32_P528311
GO:0005515
GO:0005576
GO:0005886
GO:0007166
GO:0009897
GO:0009986
GO:0010977
GO:0016020
GO:0022038
GO:0030424
GO:0030425
GO:0031103
GO:0038023
GO:0042995
GO:0043005
GO:0043204
GO:0045121
GO:0048856
GO:0051965
GO:0070062
GO:0098552
HMNXSV003055589
Hs.150898.0.A1_3p_at
ILMN_1725098
TC11000464.hg
Participates
as a member of
GPI-anchored proteins [plasma membrane] (Homo sapiens)
Other forms of this molecule
cleaved GPI-RTN4RL2 [extracellular region]
Inferred To
Fili [plasma membrane]
(Drosophila melanogaster)
Homologues of GPI-RTN4RL2 [plasma membrane]
(Drosophila melanogaster)
RTN4RL2 [plasma membrane]
(Bos taurus)
RTN4RL2 [plasma membrane]
(Canis familiaris)
RTN4RL2 [plasma membrane]
(Gallus gallus)
Rtn4rl2 [plasma membrane]
(Mus musculus)
Rtn4rl2 [plasma membrane]
(Rattus norvegicus)
ltl [plasma membrane]
(Drosophila melanogaster)
rtn4rl2b [plasma membrane]
(Danio rerio)
lbk [plasma membrane]
(Drosophila melanogaster)
Modified Residues
Name
L-cysteine amide (GPI-anchor amidated amino acid carboxyl end residue(1−)) at 390
Coordinate
390
Modification
GPI-anchor amidated amino acid carboxyl end residue(1−)
PsiMod Name
L-cysteine amide
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to L-cysteine amide.
Cross References
RefSeq
NP_848665.1
ENSEMBL
ENSP00000335397
,
ENST00000395120
,
ENST00000335099
,
ENSG00000186907
,
ENSP00000378552
OpenTargets
ENSG00000186907
GeneCards
RTN4RL2
HPA
ENSG00000186907-RTN4RL2
PRO
Q86UN3
Pharos - Targets
Q86UN3
GlyGen
Q86UN3
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P17931 LGALS3
3
LGALS3 [plasma membrane]
(R-HSA-879445)
LGALS3 [ficolin-1-rich granule membrane]
(R-HSA-6803307)
LGALS3 [secretory granule membrane]
(R-HSA-6803327)
0.527
3
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