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GPI-NEGR1 [plasma membrane]
Stable Identifier
R-HSA-8940719
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Neuronal growth regulator 1, NEGR1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Post-translational modification: synthesis of GPI-anchored proteins (Homo sapiens)
GPLD1 hydrolyses GPI-anchors from proteins (Homo sapiens)
GPI-anchored proteins [plasma membrane] (Homo sapiens)
GPI-NEGR1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7Z3B1 NEGR1
Gene Names
NEGR1, IGLON4, UNQ2433/PRO4993
Chain
signal peptide:1-37, chain:38-324, propeptide:325-354
Reference Genes
BioGPS Gene:257194 NEGR1
COSMIC (genes):NEGR1 NEGR1
CTD Gene:257194 NEGR1
dbSNP Gene:257194 NEGR1
ENSEMBL:ENSG00000172260 NEGR1
ENSEMBL_homo_sapiens_GENE:ENSG00000172260.15 NEGR1
HGNC:17302 NEGR1
KEGG Gene (Homo sapiens):257194 NEGR1
Monarch:257194 NEGR1
NCBI Gene:257194 NEGR1
OMIM:613173 NEGR1
UCSC:Q7Z3B1 NEGR1
Reference Transcript
RefSeq:NM_173808.2 NEGR1
Other Identifiers
11734770_a_at
11744915_a_at
11748179_a_at
1553194_PM_at
1553194_at
16688506
229461_PM_x_at
229461_x_at
239548_PM_at
239548_at
2418073
2418075
2418077
2418079
2418080
2418081
2418082
2418083
2418102
2418104
2418122
2418123
2418130
2418139
2418140
2418153
2418172
2418173
243357_PM_at
243357_at
257194
42749_at
62158_at
7916986
89484_at
A_23_P396800
A_33_P3341970
GE549025
GE88524
GO:0005515
GO:0005576
GO:0005886
GO:0007155
GO:0007626
GO:0007631
GO:0010976
GO:0016020
GO:0030154
GO:0030425
GO:0031175
GO:0034330
GO:0043025
GO:0048856
GO:0051963
GO:0098552
GO:0098609
HMNXSV003033248
Hs.153846.0.A1_3p_at
Hs.203838.0.A1_3p_at
Hs.296235.0.A1_3p_at
Hs2.299916.1.S1_3p_s_at
ILMN_1697804
PH_hs_0026466
TC01002777.hg
Participates
as a member of
GPI-anchored proteins [plasma membrane] (Homo sapiens)
Other forms of this molecule
cleaved GPI-NEGR1 [extracellular region]
Inferred To
Ama [plasma membrane]
(Drosophila melanogaster)
NEGR1 [plasma membrane]
(Bos taurus)
NEGR1 [plasma membrane]
(Canis familiaris)
NEGR1 [plasma membrane]
(Sus scrofa)
GPI-NEGR1 [plasma membrane]
(Gallus gallus)
Negr1 [plasma membrane]
(Mus musculus)
Negr1 [plasma membrane]
(Rattus norvegicus)
Modified Residues
Name
glycine amide (GPI-anchor amidated amino acid carboxyl end residue(1−)) at 324
Coordinate
324
Modification
GPI-anchor amidated amino acid carboxyl end residue(1−)
PsiMod Name
glycine amide
PsiMod Definition
A protein modification that effectively converts a glycine residue to glycine amide.
Cross References
RefSeq
NP_776169.2
OpenTargets
ENSG00000172260
GeneCards
Q7Z3B1
HPA
ENSG00000172260-NEGR1
Ensembl
ENST00000306821
,
ENSG00000172260
,
ENSP00000350364
,
ENST00000357731
,
ENSP00000305938
PRO
Q7Z3B1
Pharos - Targets
Q7Z3B1
PDB
6DLD
,
6U6T
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P61916 NPC2
3
NPC2 [lysosomal lumen]
(R-HSA-8876488)
NPC2 [extracellular region]
(R-HSA-6806224)
NPC2 [azurophil granule lumen]
(R-HSA-6799163)
0.639
9
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