Reactome | REEP1 [endoplasmic reticulum membrane]

REEP1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-8939766

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Receptor expression-enhancing protein 1, REEP1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9NV29 TM100

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External Reference Information

External Reference

UniProt:Q9H902 REEP1

Gene Names

REEP1, C2orf23, SPG31

Chain

chain:1-201

Reference Genes

BioGPS Gene:65055 REEP1

COSMIC (genes):REEP1 REEP1

CTD Gene:65055 REEP1

dbSNP Gene:65055 REEP1

ENSEMBL:ENSG00000068615 REEP1

ENSEMBL_homo_sapiens_GENE:ENSG00000068615.20 REEP1

HGNC:25786 REEP1

KEGG Gene (Homo sapiens):65055 REEP1

Monarch:65055 REEP1

NCBI Gene:65055 REEP1

OMIM:609139 REEP1

UCSC:Q9H902 REEP1

Reference Transcript

Other Identifiers

11719074_at

11719075_s_at

11719076_a_at

11751455_a_at

11751456_x_at

204364_PM_s_at

204364_s_at

204365_PM_s_at

204365_s_at

2562731

2562732

2562733

2562734

2562735

2562736

2562737

2562738

2562739

2562756

2562766

2562769

2562773

2562774

2562786

2562787

2562788

36096_at

65055

8053551

A_23_P96285

GE56368

GO:0005515

GO:0005737

GO:0005739

GO:0005783

GO:0005789

GO:0005856

GO:0005881

GO:0008017

GO:0008092

GO:0016020

GO:0031849

GO:0031966

GO:0043226

GO:0051205

GO:0061024

GO:0071782

GO:0071786

HMNXSV003007980

HMNXSV003029866

Hs.7358.0.S1_3p_a_at

ILMN_1733746

PH_hs_0000763

TC02002055.hg

g12597656_3p_a_at

This entity regulates

Positively

RTP1S:RTP2:underrepresented Olfactory Receptor translocates from the endoplasmic reticulum membrane to the plasma membrane (Homo sapiens)

Cross References

RefSeq

NP_075063.1, NP_001158204.1, NP_001158203.1, NP_001158202.1

OpenTargets

ENSG00000068615

HPA

ENSG00000068615-REEP1

GeneCards

Q9H902

Ensembl

ENST00000535845, ENSP00000392197, ENST00000541910, ENST00000453231, ENST00000165698, ENSP00000437567, ENSP00000165698, ENSP00000442681, ENSG00000068615

PRO

Q9H902

Pharos - Targets

Q9H902

Orphanet

15197

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H1C4 UNC93B1	4	UNC93B1 [Golgi membrane] (R-HSA-1679064) UNC93B1 [endoplasmic reticulum membrane] (R-HSA-1678930) UNC93B1 P345Pfs103 [endoplasmic reticulum membrane] (R-HSA-9628866) UNC93B1 L230Afs188 [endoplasmic reticulum membrane] (R-HSA-9628869)	0.556	3
UniProt:P21291 CSRP1	1	CSRP1 [nucleoplasm] (R-HSA-5660398)	0.556	3
UniProt:Q69YG0 TMM42			0.556	3
UniProt:O15400 STX7			0.556	3
UniProt:P78369 CLDN10	2	CLDN10 [plasma membrane] (R-HSA-420008) CLDN10 [cell junction] (R-HSA-421226)	0.556	3
UniProt:Q9NV29 TM100			0.556	3
UniProt:Q5BJF2 SGMR2			0.556	3
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.527	2
UniProt:O95274 LYPD3	2	cleaved GPI-LYPD3 [extracellular region] (R-HSA-8941013) GPI-LYPD3 [plasma membrane] (R-HSA-8940752)	0.527	2
UniProt:O15162 PLS1			0.527	4
UniProt:Q16322 KCNA10	1	KCNA10 [plasma membrane] (R-HSA-977480)	0.527	2
UniProt:P56539 CAV3	1	CAV3 [plasma membrane] (R-HSA-1368135)	0.527	2
UniProt:Q9H6H4 REEP4			0.527	4

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