Reactome | REEP1 [endoplasmic reticulum membrane]

REEP1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-8939766

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Receptor expression-enhancing protein 1, REEP1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H902 REEP1

Gene Names

REEP1, C2orf23, SPG31

Chain

chain:1-201

Reference Genes

BioGPS Gene:65055 REEP1

COSMIC (genes):REEP1 REEP1

CTD Gene:65055 REEP1

dbSNP Gene:65055 REEP1

ENSEMBL:ENSG00000068615 REEP1

HGNC:25786 REEP1

Monarch:65055 REEP1

NCBI Gene:65055 REEP1

OMIM:609139 REEP1

UCSC:Q9H902 REEP1

Reference Transcript

Other Identifiers

11719074_at

11719075_s_at

11719076_a_at

11751455_a_at

11751456_x_at

204364_PM_s_at

204364_s_at

204365_PM_s_at

204365_s_at

2562731

2562732

2562733

2562734

2562735

2562736

2562737

2562738

2562739

2562742

2562743

2562746

2562747

2562749

2562750

2562756

2562761

2562762

2562765

2562766

2562769

2562770

2562773

2562774

2562783

2562784

2562785

2562786

2562787

2562788

36096_at

65055

8053551

A_23_P96285

GE56368

GO:0005515

GO:0005737

GO:0005739

GO:0005783

GO:0005789

GO:0005881

GO:0008017

GO:0008092

GO:0016020

GO:0031849

GO:0031966

GO:0043226

GO:0051205

GO:0071782

GO:0071786

HMNXSV003007980

HMNXSV003029866

Hs.7358.0.S1_3p_a_at

ILMN_1733746

PH_hs_0000763

TC02002055.hg

g12597656_3p_a_at

This entity regulates

Positively

RTP1S:RTP2:underrepresented Olfactory Receptor translocates from the endoplasmic reticulum membrane to the plasma membrane (Homo sapiens)

Cross References

ENSEMBL

ENSP00000437567, ENSP00000442681, ENST00000165698, ENST00000535845, ENST00000541910, ENSP00000165698, ENST00000453231, ENSP00000392197

OpenTargets

ENSG00000068615

HPA

ENSG00000068615-REEP1

PRO

Q9H902

Pharos - Targets

Q9H902

Orphanet

REEP1

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5BJF2 SGMR2			0.556	3
UniProt:Q9NV29 TM100			0.556	3
UniProt:P21291 CSRP1	1	CSRP1 [nucleoplasm] (R-HSA-5660398)	0.556	3
UniProt:Q9H1C4 UNC93B1	4	UNC93B1 [Golgi membrane] (R-HSA-1679064) UNC93B1 [endoplasmic reticulum membrane] (R-HSA-1678930) UNC93B1 P345Pfs103 [endoplasmic reticulum membrane] (R-HSA-9628866) UNC93B1 L230Afs188 [endoplasmic reticulum membrane] (R-HSA-9628869)	0.556	3
UniProt:P78369 CLDN10	2	CLDN10 [plasma membrane] (R-HSA-420008) CLDN10 [cell junction] (R-HSA-421226)	0.556	3
UniProt:O15400 STX7			0.556	3
UniProt:Q69YG0 TMM42			0.556	3
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.527	2
UniProt:O95274 LYPD3	2	cleaved GPI-LYPD3 [extracellular region] (R-HSA-8941013) GPI-LYPD3 [plasma membrane] (R-HSA-8940752)	0.527	2
UniProt:O15162 PLS1			0.527	4
UniProt:Q9H6H4 REEP4			0.527	4
UniProt:P56539 CAV3	1	CAV3 [plasma membrane] (R-HSA-1368135)	0.527	2
UniProt:Q16322 KCNA10	1	KCNA10 [plasma membrane] (R-HSA-977480)	0.527	2