Reactome | REEP4 [endoplasmic reticulum membrane]

REEP4 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-8939764

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Receptor expression-enhancing protein 4, REEP4_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H6H4 REEP4

Gene Names

REEP4, C8orf20, PP432

Chain

chain:1-257

Reference Genes

BioGPS Gene:80346 REEP4

COSMIC (genes):REEP4 REEP4

CTD Gene:80346 REEP4

dbSNP Gene:80346 REEP4

ENSEMBL:ENSG00000168476 REEP4

HGNC:26176 REEP4

KEGG Gene (Homo sapiens):80346 REEP4

Monarch:80346 REEP4

NCBI Gene:80346 REEP4

OMIM:609349 REEP4

UCSC:Q9H6H4 REEP4

Reference Transcript

Other Identifiers

0002030403

11718496_a_at

11748637_a_at

17075314

218777_at

3127335

3127336

3127337

3127338

3127339

3127340

3127343

3127345

3127346

3127348

3127350

3127351

43854_at

47591_at

80346

8149673

A_23_P96209

GE87753

GO:0000278

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005783

GO:0005789

GO:0005856

GO:0005874

GO:0005881

GO:0006998

GO:0007049

GO:0007084

GO:0008017

GO:0008092

GO:0008150

GO:0016020

GO:0016021

GO:0043226

GO:0051301

GO:0061024

GO:0071782

GO:0071786

ILMN_1729611

PH_hs_0015031

PH_hs_0040457

TC08001034.hg

g13376835_3p_at

Participant Of

hasCandidate

REEPs [endoplasmic reticulum membrane]

Inferred To

Reep4 [endoplasmic reticulum membrane] (Mus musculus)

Reep4 [endoplasmic reticulum membrane] (Rattus norvegicus)

REEP4 [endoplasmic reticulum membrane] (Canis familiaris)

REEP4 [endoplasmic reticulum membrane] (Sus scrofa)

Cross References

RefSeq

NP_001303894.1, NP_001303893.1, NP_079508.2

OpenTargets

ENSG00000168476

HPA

ENSG00000168476-REEP4

GeneCards

Q9H6H4

Ensembl

ENSG00000168476, ENSP00000333889, ENSP00000303482, ENST00000334530, ENST00000306306

PRO

Q9H6H4

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q01628 IFITM3	1	IFITM3 [plasma membrane] (R-HSA-1015688)	0.556	3
UniProt:Q13277 STX3	1	STX3 [plasma membrane] (R-HSA-449131)	0.556	3
UniProt:O43639 NCK2	1	NCK2 [cytosol] (R-HSA-204885)	0.556	3
UniProt:O15155 BET1	3	BET1 [transport vesicle] (R-HSA-6808719) BET1 [Golgi membrane] (R-HSA-6807743) BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688142)	0.556	3
UniProt:Q9Y6X1 SERP1	2	SERP1 [cytosol] (R-HSA-5250574) SERP1 [endoplasmic reticulum membrane] (R-HSA-381045)	0.556	3
UniProt:Q13190 STX5	5	STX5 [endoplasmic reticulum membrane] (R-HSA-5689474) STX5 [Golgi membrane] (R-HSA-6807771) STX5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688157) STX5 [ER to Golgi transport vesicle membrane] (R-HSA-5689838) STX5 [cytosol] (R-HSA-9613991)	0.556	3
UniProt:Q01453 PMP22	1	PMP22 [plasma membrane] (R-HSA-9615623)	0.556	3
UniProt:O95070 YIF1A	1	YIF1A [endoplasmic reticulum membrane] (R-HSA-535599)	0.556	3
UniProt:Q9Y5Z9 UBIAD1	1	UBIAD1 [endoplasmic reticulum membrane] (R-HSA-2980965)	0.556	3
UniProt:Q9Y5Y5 PEX16	2	PEX16 [cytosol] (R-HSA-9603790) PEX16 [peroxisomal membrane] (R-HSA-9603805)	0.556	3
UniProt:O75379 VAMP4	4	VAMP4 [trans-Golgi network membrane] (R-HSA-6811021) VAMP4 [transport vesicle] (R-HSA-6811023) VAMP4 [plasma membrane] (R-HSA-8864461) VAMP4 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869133)	0.556	3
UniProt:P21964 COMT	2	COMT [cytosol] (R-HSA-175974) COMT [plasma membrane] (R-HSA-379386)	0.556	3
UniProt:Q14534 SQLE	1	SQLE [endoplasmic reticulum membrane] (R-HSA-191395)	0.556	3
UniProt:O75396 SEC22B	6	SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.556	3
UniProt:Q9H2F3 HSD3B7	1	HSD3B7 [endoplasmic reticulum membrane] (R-HSA-193441)	0.556	3
UniProt:Q9Y584 TIMM22	3	TIMM22 [mitochondrial intermembrane space] (R-HSA-1267958) TIMM22 [mitochondrial inner membrane] (R-HSA-1252098) TIMM22 [cytosol] (R-HSA-1267997)	0.556	3
UniProt:Q07817 BCL2L1	2	BCL2L1 [mitochondrial outer membrane] (R-HSA-114236) BCL2L1 [cytosol] (R-HSA-50771)	0.556	3
UniProt:Q8IWU4 SLC30A8	1	SLC30A8 [secretory granule membrane] (R-HSA-437106)	0.556	3

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