Reactome | REEP4 [endoplasmic reticulum membrane]

REEP4

Stable Identifier

R-HSA-8939764

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Receptor expression-enhancing protein 4, REEP4_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H6H4 REEP4

Gene Names

REEP4, C8orf20, PP432

Chain

chain:1-257

Reference Genes

BioGPS Gene:80346 REEP4

COSMIC (genes):REEP4 REEP4

CTD Gene:80346 REEP4

dbSNP Gene:80346 REEP4

ENSEMBL:ENSG00000168476 REEP4

HGNC:26176 REEP4

KEGG Gene (Homo sapiens):hsa:80346 REEP4

Monarch:80346 REEP4

NCBI Gene:80346 REEP4

OMIM:609349 REEP4

UCSC:Q9H6H4 REEP4

Reference Transcript

Other Identifiers

0002030403

11718496_a_at

11748637_a_at

17075314

218777_at

3127335

3127336

3127337

3127338

3127339

3127340

3127343

3127345

3127346

3127348

3127350

3127351

42683

43854_at

47591_at

80346

8149673

A_23_P96209

AAG17256

AAH13048

AAH50622

AAT70687

AC105206

AF218014

AK025899

AK025930

AK172846

AY562242

BAB15274

BAB15285

BAD18810

BC013048

BC050622

CAG33634

CCDS6024

CCDS83257

CH471080

CR457353

E5RGS2

E5RIB5

EAW63710

EAW63715

ENSG00000168476

ENSP00000303482

ENSP00000333889

ENST00000306306

ENST00000334530

EntrezGene:80346

g13376835_3p_at

GE87753

GO:0000278

GO:0003674

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005783

GO:0005789

GO:0005856

GO:0005874

GO:0006998

GO:0007049

GO:0007084

GO:0008017

GO:0008092

GO:0008150

GO:0016020

GO:0016021

GO:0043226

GO:0051301

GO:0061024

HGNC:26176

HPA042683

ILMN_1729611

IPR004345

MIM:609349

NM_001316965

NM_025232

NP_001303894

NP_079508

PF03134

PH_hs_0015031

PH_hs_0040457

REEP4

REEP4-201

REEP4-202

TC08001034.hg

uc003xau.2

uc010ltt.2

UPI000006E42E

UPI000018CEB9

Participant Of

hasCandidate

REEPs [endoplasmic reticulum membrane]

Inferred To

REEP4 [endoplasmic reticulum membrane] (Bos taurus)

REEP4 [endoplasmic reticulum membrane] (Canis familiaris)

REEP4 [endoplasmic reticulum membrane] (Mus musculus)

REEP4 [endoplasmic reticulum membrane] (Rattus norvegicus)

REEP4 [endoplasmic reticulum membrane] (Sus scrofa)

REEP4 [endoplasmic reticulum membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_001303894.1, NP_079508.2, NP_001303893.1

GeneCards

Q9H6H4

PRO

Q9H6H4

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8IWU4 SLC30A8	1	SLC30A8 [secretory granule membrane] (R-HSA-437106)	0.488	2
UniProt:O43639 NCK2	1	NCK2 [cytosol] (R-HSA-204885)	0.488	2
UniProt:Q9Y5Z9 UBIAD1	1	UBIAD1 [endoplasmic reticulum membrane] (R-HSA-2980965)	0.488	2
UniProt:Q13190 STX5	4	STX5 [endoplasmic reticulum membrane] (R-HSA-5689474) STX5 [Golgi membrane] (R-HSA-6807771) STX5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688157) STX5 [ER to Golgi transport vesicle membrane] (R-HSA-5689838)	0.488	2
UniProt:Q07817 BCL2L1	1	BCL2L1 [mitochondrial outer membrane] (R-HSA-114236)	0.488	2
UniProt:Q13277 STX3	1	STX3 [plasma membrane] (R-HSA-449131)	0.488	2
UniProt:O75379 VAMP4	4	VAMP4 [trans-Golgi network membrane] (R-HSA-6811021) VAMP4 [transport vesicle] (R-HSA-6811023) VAMP4 [plasma membrane] (R-HSA-8864461) VAMP4 [clathrin-coated vesicle membrane] (R-HSA-8869133)	0.488	2
UniProt:Q9H2F3 HSD3B7	1	HSD3B7 [endoplasmic reticulum membrane] (R-HSA-193441)	0.488	2
UniProt:O75396 SEC22B	6	SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.488	2
UniProt:Q9Y584 TIMM22	3	TIMM22 [mitochondrial intermembrane space] (R-HSA-1267958) TIMM22 [mitochondrial inner membrane] (R-HSA-1252098) TIMM22 [cytosol] (R-HSA-1267997)	0.488	2
UniProt:O15155 BET1	3	BET1 [transport vesicle] (R-HSA-6808719) BET1 [Golgi membrane] (R-HSA-6807743) BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688142)	0.488	2
UniProt:P21964 COMT	2	COMT [cytosol] (R-HSA-175974) COMT [plasma membrane] (R-HSA-379386)	0.488	2
UniProt:O95070 YIF1A	1	YIF1A [endoplasmic reticulum membrane] (R-HSA-535599)	0.488	2
UniProt:Q14534 SQLE	1	SQLE [endoplasmic reticulum membrane] (R-HSA-191395)	0.488	2
UniProt:Q9Y6X1 SERP1	2	SERP1 [endoplasmic reticulum membrane] (R-HSA-381045) SERP1 [cytosol] (R-HSA-5250574)	0.488	2
UniProt:Q01628 IFITM3	1	IFITM3 [plasma membrane] (R-HSA-1015688)	0.488	2