RUNX1 binds the CR1 gene promoter

Stable Identifier
R-HSA-8939082
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
RUNX1 binds the CR1 gene promoter
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The RUNX1:CBFB complex binds the promoter of the CR1 (CD35) gene, encoding Complement receptor type 1 (Kim et al. 1999, Rho et al. 2002).
Literature References
PubMed ID Title Journal Year
10533284 AML1, the target of chromosomal rearrangements in human leukemia, regulates the expression of human complement receptor type 1 (CR1) gene

Choe, SY, Kim, JH, Rho, JK, Lee, S

Int. J. Biochem. Cell Biol. 1999
12220513 Correlation between cellular localization of TEL/AML1 fusion protein and repression of AML1-mediated transactivation of CR1 gene

Choe, SY, Rho, JK, Kim, JH, Yu, J

Biochem. Biophys. Res. Commun. 2002
Participants
Input
Output
Participates
as an event of
Authored
Orlic-Milacic, M  (2016-09-14)
Reviewed
Chuang, LS  (2016-12-20)
Ito, Y  (2016-12-20)
Created
Orlic-Milacic, M  (2016-09-15)
Cite Us!