Binding of the RUNX1:CBFB complex to the promoter of the PRKCB gene, encoding Protein kinase C-beta, stimulates PRKCB transcription. RUNX1-mediated upregulation of PRKCB expression may contribute to apoptosis of myeloid cells (Hug et al. 2004).
Hug, BA, Ahmed, N, Robbins, JA, Lazar, MA
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