PML binds RUNX1

Stable Identifier
R-HSA-8938887
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
RUNX1 interacts with PML, and the interaction involves the C-terminus of PML and the C-terminus of RUNX1. PML targets RUNX1 to nuclear bodies, which may be important for activation of some RUNX1 target genes, such as CSF2 (GM-CSF) (Nguyen et al. 2005).
Literature References
PubMed ID Title Journal Year
15331439 Physical and functional link of the leukemia-associated factors AML1 and PML

Pandolfi, PP, Nguyen, LA, Ohki, M, Tagata, Y, Kitabayashi, I, Aikawa, Y

Blood 2005
Participants
Participates
Orthologous Events
Authored
Reviewed
Created
Cite Us!