miR-20a binds RUNX1 mRNA

Stable Identifier
R-HSA-8938487
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
miR-20a binds RUNX1 mRNA
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

MicroRNA miR-20a binds the 3' UTR of the RUNX1 mRNA. As miR-20a does not affect RUNX1 mRNA levels, it presumably function as part of the nonendonucleolytic RISC (Fontana et al. 2007).

Literature References
PubMed ID Title Journal Year
17589498 MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation

Fontana, L, Pelosi, E, Greco, P, Racanicchi, S, Testa, U, Liuzzi, F, Croce, CM, Brunetti, E, Grignani, F, Peschle, C

Nat. Cell Biol. 2007
Participants
Input
Output
Participant Of
hasEvent
Authored
Orlic-Milacic, M  (2016-09-14)
Reviewed
Ito, Y  (2016-12-20)
Chuang, LS  (2016-12-20)
Created
Orlic-Milacic, M  (2016-09-09)