RUNX1:CBFB binds the LGALS3 gene promoter

Stable Identifier
R-HSA-8938389
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
RUNX1:CBFB binds the LGALS3 gene promoter
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The RUNX1:CBFB complex binds to the RUNX1 response element in the promoter of the LGALS3 gene, encoding Galectin-3 (Zhang et al. 2009).

Literature References
PubMed ID Title Journal Year
19020999 RUNX1 and RUNX2 upregulate Galectin-3 expression in human pituitary tumors

Coonse, K, Zhang, HY, Jin, L, Tanizaki, Y, Lloyd, RV, Raz, A, Ruebel, KH, Stilling, GA

Endocrine 2009
Participants
Input
Output
Participates
as an event of
Authored
Orlic-Milacic, M  (2016-09-14)
Reviewed
Chuang, LS  (2016-12-20)
Ito, Y  (2016-12-20)
Created
Orlic-Milacic, M  (2016-09-09)
Cite Us!