RUNX1:CBFB binds the MYL9 gene promoter

Stable Identifier
R-HSA-8938199
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RUNX1:CBFB binds the MYL9 gene promoter
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The RUNX1:CBFB complex binds to four RUNX1 response elements in the promoter of the MYL9 gene, encoding Myosin regulatory light polypeptide 9, which functions as the regulatory subunit of the myosin complex (Jalagadugula et al. 2010).
Literature References
PubMed ID Title Journal Year
20876458 Regulation of platelet myosin light chain (MYL9) by RUNX1: implications for thrombocytopenia and platelet dysfunction in RUNX1 haplodeficiency

Kaur, G, Dhanasekaran, DN, Rao, AK, Goldfinger, LE, Mao, G, Jalagadugula, G

Blood 2010
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Authored
Orlic-Milacic, M  (2016-09-14)
Reviewed
Chuang, LS  (2016-12-20)
Ito, Y  (2016-12-20)
Created
Orlic-Milacic, M  (2016-09-08)
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