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SERPINB13 [lysosomal lumen]
Stable Identifier
R-HSA-8938045
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal lumen
Synonyms
Serpin B13, SPB13_HUMAN, HaCaT UV-repressible serpin, Hurpin, Headpin, Peptidase inhibitor 13, PI-13, Proteinase inhibitor 13, PI13
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX1 (Homo sapiens)
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes (Homo sapiens)
SERPINB13 binds CTSK (Homo sapiens)
CTSK:SERPINB13 [lysosomal lumen] (Homo sapiens)
SERPINB13 [lysosomal lumen] (Homo sapiens)
SERPINB13 [lysosomal lumen] (Homo sapiens)
SERPINB13 binds cathepsin L (Homo sapiens)
SERPINB13 [lysosomal lumen] (Homo sapiens)
SERPINB13:cathepsin L [lysosomal lumen] (Homo sapiens)
SERPINB13 [lysosomal lumen] (Homo sapiens)
SERPINB13 gene expression is inhibited by RUNX1:CBFB (Homo sapiens)
SERPINB13 [lysosomal lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UIV8 SERPINB13
Gene Names
SERPINB13, PI13
Chain
chain:1-391
Reference Genes
BioGPS Gene:5275 SERPINB13
COSMIC (genes):SERPINB13 SERPINB13
CTD Gene:5275 SERPINB13
dbSNP Gene:5275 SERPINB13
ENSEMBL:ENSG00000197641 SERPINB13
ENSEMBL_homo_sapiens_GENE:ENSG00000197641.12 SERPINB13
HGNC:8944 SERPINB13
Monarch:5275 SERPINB13
NCBI Gene:5275 SERPINB13
OMIM:604445 SERPINB13
UCSC:Q9UIV8 SERPINB13
Reference Transcript
RefSeq:NM_012397.3 SERPINB13
RefSeq:NM_001307923.1 SERPINB13
Other Identifiers
11735726_a_at
11735727_at
11751053_a_at
16852833
211361_PM_s_at
211361_s_at
211362_PM_s_at
211362_s_at
216258_PM_s_at
216258_s_at
217272_PM_s_at
217272_s_at
3791851
3791854
3791855
3791858
3791859
3791863
3791864
3791866
3791867
3791868
5275
8021603
A_14_P130338
A_23_P119015
A_23_P432978
A_24_P104689
A_33_P3279019
GE63207
GO:0002020
GO:0004867
GO:0004869
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005737
GO:0005764
GO:0005773
GO:0005829
GO:0009411
GO:0010951
GO:0012501
GO:0016607
GO:0030162
GO:0030414
GO:0043202
GO:0043226
GO:0070062
GO:0098772
GO:1902173
HMNXSV003028917
Hs.241407.0.S2_3p_a_at
Hs.241407.2.S1_3p_a_at
PH_hs_0040676
TC18000228.hg
g5911368_3p_a_at
Participates
as a component of
SERPINB13:cathepsin L [lysosomal lumen] (Homo sapiens)
CTSK:SERPINB13 [lysosomal lumen] (Homo sapiens)
as an input of
SERPINB13 binds cathepsin L (Homo sapiens)
SERPINB13 binds CTSK (Homo sapiens)
as an output of
SERPINB13 gene expression is inhibited by RUNX1:CBFB (Homo sapiens)
Inferred To
Spn47C [lysosomal lumen]
(Drosophila melanogaster)
nec [lysosomal lumen]
(Drosophila melanogaster)
Spn75F [lysosomal lumen]
(Drosophila melanogaster)
Spn88Eb [lysosomal lumen]
(Drosophila melanogaster)
Spn27A [lysosomal lumen]
(Drosophila melanogaster)
Spn31A [lysosomal lumen]
(Drosophila melanogaster)
srp-2 [lysosomal lumen]
(Caenorhabditis elegans)
Serpinb13 [lysosomal lumen]
(Mus musculus)
Serpinb13 [lysosomal lumen]
(Rattus norvegicus)
srp-7 [lysosomal lumen]
(Caenorhabditis elegans)
Spn42Db [lysosomal lumen]
(Drosophila melanogaster)
srp-1 [lysosomal lumen]
(Caenorhabditis elegans)
Spn28F [lysosomal lumen]
(Drosophila melanogaster)
Spn28Db [lysosomal lumen]
(Drosophila melanogaster)
srp-8 [lysosomal lumen]
(Caenorhabditis elegans)
Dmel\CG43366 [lysosomal lumen]
(Drosophila melanogaster)
Spn53F [lysosomal lumen]
(Drosophila melanogaster)
SERPINB13 [lysosomal lumen]
(Bos taurus)
SERPINB13 [lysosomal lumen]
(Caenorhabditis elegans)
SERPINB13 [lysosomal lumen]
(Canis familiaris)
SERPINB13 [lysosomal lumen]
(Gallus gallus)
SERPINB13 [lysosomal lumen]
(Sus scrofa)
Spn42De [lysosomal lumen]
(Drosophila melanogaster)
Spn88Ea [lysosomal lumen]
(Drosophila melanogaster)
si:dkey-177p2.11 [lysosomal lumen]
(Danio rerio)
Spn43Ab [lysosomal lumen]
(Drosophila melanogaster)
srp-6 [lysosomal lumen]
(Caenorhabditis elegans)
Spn38F [lysosomal lumen]
(Drosophila melanogaster)
Acp76A [lysosomal lumen]
(Drosophila melanogaster)
Spn42Dd [lysosomal lumen]
(Drosophila melanogaster)
Spn100A [lysosomal lumen]
(Drosophila melanogaster)
Spn28B [lysosomal lumen]
(Drosophila melanogaster)
Spn42Da [lysosomal lumen]
(Drosophila melanogaster)
Homologues of SERPINB13 [lysosomal lumen]
(Caenorhabditis elegans)
Homologues of SERPINB13 [lysosomal lumen]
(Danio rerio)
Homologues of SERPINB13 [lysosomal lumen]
(Drosophila melanogaster)
Homologues of SERPINB13 [lysosomal lumen]
(Gallus gallus)
si:dkey-177p2.13 [lysosomal lumen]
(Danio rerio)
Spn43Aa [lysosomal lumen]
(Drosophila melanogaster)
Spn43Ad [lysosomal lumen]
(Drosophila melanogaster)
Spn85F [lysosomal lumen]
(Drosophila melanogaster)
Spn55B [lysosomal lumen]
(Drosophila melanogaster)
Spn28Da [lysosomal lumen]
(Drosophila melanogaster)
Spn42Dc [lysosomal lumen]
(Drosophila melanogaster)
serpinb4 [lysosomal lumen]
(Xenopus tropicalis)
srp-3 [lysosomal lumen]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_036529.1
,
NP_001294852.1
OpenTargets
ENSG00000197641
GeneCards
Q9UIV8
HPA
ENSG00000197641-SERPINB13
Ensembl
ENSG00000197641
,
ENST00000344731
,
ENSP00000341584
PRO
Q9UIV8
Pharos - Targets
Q9UIV8
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15700 DLG2
2
DLG2 [plasma membrane]
(R-HSA-9610662)
DLG2 [cytosol]
(R-HSA-6794230)
0.556
3
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