RUNX3 binds SRC

Stable Identifier
R-HSA-8937792
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
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RUNX3 binds SRC
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Activated SRC binds to RUNX3 in the cytosol. The interaction involves the Runt domain of RUNX3 (Goh et al. 2010).

Literature References
PubMed ID Title Journal Year
20100835 Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm

Goh, YM, Cinghu, S, Hong, ET, Lee, YS, Kim, JH, Jang, JW, Li, YH, Chi, XZ, Lee, KS, Wee, H, Ito, Y, Oh, BC, Bae, SC

J. Biol. Chem. 2010
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Orthologous Events
RUNX3 binds SRC (Bos taurus)
RUNX3 binds SRC (Caenorhabditis elegans)
RUNX3 binds SRC (Canis familiaris)
RUNX3 binds SRC (Danio rerio)
RUNX3 binds SRC (Drosophila melanogaster)
RUNX3 binds SRC (Gallus gallus)
RUNX3 binds SRC (Mus musculus)
RUNX3 binds SRC (Rattus norvegicus)
RUNX3 binds SRC (Sus scrofa)
RUNX3 binds SRC (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2016-12-13)
Reviewed
Ito, Y  (2017-01-31)
Chuang, LS  (2017-01-31)
Created
Orlic-Milacic, M  (2016-09-06)
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