Reactome | GUCY2C [plasma membrane]

GUCY2C [plasma membrane]

Stable Identifier

R-HSA-8936203

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Heat-stable enterotoxin receptor, GUC2C_HUMAN

Icon

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Bacterial Infection Pathways (Homo sapiens)
    - Uptake and actions of bacterial toxins (Homo sapiens)
      - Intestinal infectious diseases (Homo sapiens)
        
        GUCY2C trimer binds sta1 (Homo sapiens)
        
        GUCY2C trimer [plasma membrane] (Homo sapiens)
        
        GUCY2C [plasma membrane] (Homo sapiens)
        
        GUCY2C trimer:sta1 [plasma membrane] (Homo sapiens)
        
        GUCY2C trimer [plasma membrane] (Homo sapiens)
        
        GUCY2C [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P25092 GUCY2C

Gene Names

GUCY2C, GUC2C, STAR

Chain

signal peptide:1-23, chain:24-1073

Reference Genes

BioGPS Gene:2984 GUCY2C

COSMIC (genes):GUCY2C GUCY2C

COSMIC (genes):STAR GUCY2C

CTD Gene:2984 GUCY2C

dbSNP Gene:2984 GUCY2C

ENSEMBL:ENSG00000070019 GUCY2C

HGNC:4688 GUCY2C

KEGG:hsa:2984 GUCY2C

Monarch:2984 GUCY2C

NCBI Gene:2984 GUCY2C

OMIM:601330 GUCY2C

UCSC:P25092 GUCY2C

Reference Transcript

RefSeq:NM_004963.3 GUCY2C

Other Identifiers

11732646_a_at

16761745

206312_PM_at

206312_at

2984

34450_at

3445575

3445576

3445577

3445578

3445579

3445580

3445583

3445584

3445586

3445587

3445588

3445589

3445590

3445592

3445593

3445594

3445595

3445597

3445598

3445599

3445600

3445601

3445603

3445605

3445606

3445607

3445610

3445611

3445612

3445613

3445614

3445615

3445616

3445618

3445619

3445620

3445621

3445622

7961455

A_23_P76312

GE79279

GO:0001653

GO:0003824

GO:0004016

GO:0004383

GO:0004672

GO:0005515

GO:0005524

GO:0005525

GO:0005783

GO:0005789

GO:0005886

GO:0006182

GO:0006468

GO:0007168

GO:0009190

GO:0009636

GO:0009975

GO:0015643

GO:0016740

GO:0016829

GO:0016849

GO:0035556

GO:0042127

GO:0043226

GO:0055086

GO:0060089

GO:0140096

GO:1901135

HMNXSV003001937

ILMN_2144663

M73489_at

PH_hs_0022834

TC12001271.hg

TC12002772.hg

U20230_at

g4826751_3p_at

Participates

as a component of

GUCY2C trimer [plasma membrane] (Homo sapiens)

Inferred To

gucy2c [plasma membrane] (Xenopus tropicalis)

Gucy2c [plasma membrane] (Mus musculus)

Gucy2c [plasma membrane] (Rattus norvegicus)

GUCY2C [plasma membrane] (Bos taurus)

GUCY2C [plasma membrane] (Canis familiaris)

GUCY2C [plasma membrane] (Gallus gallus)

GUCY2C [plasma membrane] (Sus scrofa)

Cross References

Guide to Pharmacology - Targets

1750

ENSEMBL

ENSG00000070019, ENST00000261170, ENSP00000261170

OpenTargets

ENSG00000070019

GeneCards

GUCY2C

HPA

ENSG00000070019-GUCY2C

PRO

P25092

Pharos - Targets

P25092

GlyGen

P25092

Orphanet

GUCY2C

HMDB Protein

HMDBP01070

PDB

8GHP, 8GHO, 8FX4

Cite Us!