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GUCA2A(22-115) [extracellular region]
Stable Identifier
R-HSA-8936191
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
HMW-Guanylin, GUC2A_HUMAN
Locations in the PathwayBrowser
Expand all
Digestion and absorption (Homo sapiens)
Digestion (Homo sapiens)
GUCY2C trimer binds GUCA2A,B (Homo sapiens)
GUCA2A,B [extracellular region] (Homo sapiens)
GUCA2A(22-115) [extracellular region] (Homo sapiens)
GUCY2C trimer:GUCA2A,B [plasma membrane] (Homo sapiens)
GUCA2A,B [extracellular region] (Homo sapiens)
GUCA2A(22-115) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q02747 GUCA2A
Gene Names
GUCA2A, GUCA2
Chain
signal peptide:1-21, chain:22-115, peptide:101-115
Reference Genes
BioGPS Gene:2980 GUCA2A
COSMIC (genes):GUCA2A GUCA2A
CTD Gene:2980 GUCA2A
dbSNP Gene:2980 GUCA2A
ENSEMBL:ENSG00000197273 GUCA2A
ENSEMBL_homo_sapiens_GENE:ENSG00000197273.4 GUCA2A
HGNC:4682 GUCA2A
KEGG Gene (Homo sapiens):2980 GUCA2A
Monarch:2980 GUCA2A
NCBI Gene:2980 GUCA2A
OMIM:139392 GUCA2A
UCSC:Q02747 GUCA2A
Reference Transcript
RefSeq:NM_033553.2 GUCA2A
Other Identifiers
11731957_at
16685953
207003_PM_at
207003_at
2408833
2408834
2408835
2408836
2408837
2408839
2980
33995_at
7915404
A_23_P11968
GE79395
GO:0005179
GO:0005515
GO:0005576
GO:0007165
GO:0023052
GO:0030250
GO:0048018
GO:0098772
HMNXSV003004324
ILMN_1763749
M97496_at
TC01002569.hg
g4504208_3p_at
Participates
as a member of
GUCA2A,B [extracellular region] (Homo sapiens)
Inferred To
Guca2a [extracellular region]
(Mus musculus)
Guca2a [extracellular region]
(Rattus norvegicus)
LOC116410927 [extracellular region]
(Xenopus tropicalis)
GUCA2A [extracellular region]
(Bos taurus)
GUCA2A [extracellular region]
(Canis familiaris)
GUCA2A [extracellular region]
(Sus scrofa)
Cross References
RefSeq
NP_291031.2
OpenTargets
ENSG00000197273
GeneCards
Q02747
HPA
ENSG00000197273-GUCA2A
Ensembl
ENSG00000197273
,
ENST00000357001
,
ENSP00000349493
PRO
Q02747
Pharos - Targets
Q02747
PDB
1GNA
,
1O8R
,
1GNB
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8N661 TMEM86B
1
TMEM86B [endoplasmic reticulum membrane]
(R-HSA-8874443)
0.556
3
UniProt:O15552 FFAR2
1
FFAR2 [plasma membrane]
(R-HSA-443944)
0.556
3
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