TJP1 (ZO-1) gene expression is stimulated by RUNX1

Stable Identifier
R-HSA-8935972
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Binding of the RUNX1:CBFB complex to the promoter of the TJP1 gene stimulates transcription of the tight junction component ZO-1 (Miao et al. 2015).
Literature References
PubMed ID Title Journal Year
25452107 MiR-18a increased the permeability of BTB via RUNX1 mediated down-regulation of ZO-1, occludin and claudin-5

Xue, YX, Wang, P, Zhao, YY, Miao, YS, Ma, J, Liu, YH, Zhao, LN

Cell. Signal. 2015
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