RUNX1 forms a complex with protein arginine methyltransferase 1 (PRMT1) in a RNA- and DNA-independent manner. The interaction with PRMT1 involves the C-terminus of RUNX1. Since PRMT1 colocalizes with RUNX1 at RUNX1 target promoters, RUNX1 is shown as part of the RUNX1:CBFB complex (Zhao et al. 2008).
Menendez, S, Tempst, P, Xiao, A, Nimer, SD, Allis, CD, Erdjument-Bromage, H, Zhao, X, Pardanani, A, Jankovic, V, Zhang, J, Dunne, R, Gural, A, Huang, G
© 2023 Reactome
