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NADK2 [mitochondrial matrix]
Stable Identifier
R-HSA-8933311
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
NAD kinase 2, mitochondrial ecNumber2.7.1.23/ecNumber, NAKD2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Nicotinate metabolism (Homo sapiens)
NADK2 dimer phosphorylates NAD+ to NADP+ (Homo sapiens)
NADK2 dimer [mitochondrial matrix] (Homo sapiens)
NADK2 [mitochondrial matrix] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Mitochondrial protein degradation (Homo sapiens)
LONP1 binds mitochondrial matrix proteins (Homo sapiens)
LONP1:substrate protein (mitochondrial matrix) [mitochondrial matrix] (Homo sapiens)
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Homo sapiens)
NADK2 [mitochondrial matrix] (Homo sapiens)
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Homo sapiens)
NADK2 [mitochondrial matrix] (Homo sapiens)
LONP1 degrades mitochondrial matrix proteins (Homo sapiens)
LONP1:substrate protein (mitochondrial matrix) [mitochondrial matrix] (Homo sapiens)
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Homo sapiens)
NADK2 [mitochondrial matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q4G0N4 NADK2
Gene Names
NADK2, C5orf33, MNADK, NADKD1
Chain
transit peptide:1-62, chain:63-442
Reference Genes
BioGPS Gene:133686 NADK2
COSMIC (genes):NADK2 NADK2
CTD Gene:133686 NADK2
dbSNP Gene:133686 NADK2
ENSEMBL:ENSG00000152620 NADK2
HGNC:26404 NADK2
KEGG:hsa:133686 NADK2
Monarch:133686 NADK2
NCBI Gene:133686 NADK2
OMIM:615787 NADK2
UCSC:Q4G0N4 NADK2
Reference Transcript
RefSeq:NM_001287340.1 NADK2
RefSeq:NM_001085411.2 NADK2
RefSeq:NM_153013.4 NADK2
RefSeq:NM_001287341.1 NADK2
Other Identifiers
11733995_x_at
11733996_a_at
11746794_a_at
11746795_s_at
11753516_a_at
11754487_x_at
133686
16995281
226946_PM_at
226946_at
228594_3p_at
228594_PM_at
228594_at
229299_PM_at
229299_at
2853389
2853390
2853391
2853392
2853393
2853394
2853395
2853397
2853398
2853399
2853400
2853402
2853403
2853404
2853405
2853406
2853407
2853408
2853409
2853410
2853421
2853422
2853423
2853424
2853425
45620_at
55049_r_at
62154_at
77918_at
8111552
91651_at
A_23_P337168
A_33_P3233649
GE515682
GE86208
GO:0003824
GO:0003951
GO:0005524
GO:0005739
GO:0005759
GO:0006741
GO:0016301
GO:0016740
GO:0016773
GO:0019674
GO:0042803
GO:0043226
GO:0055086
HMNXSV003039269
Hs.46637.0.A1_3p_at
Hs.46637.1.A1_3p_at
Hs.81907.0.A1_3p_at
Hs.81907.0.A1_3p_x_at
ILMN_1698770
ILMN_1860412
PH_hs_0004681
TC05001270.hg
Participates
as a member of
Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Homo sapiens)
as a component of
NADK2 dimer [mitochondrial matrix] (Homo sapiens)
Inferred To
Nadk2 [mitochondrial matrix]
(Drosophila melanogaster)
Nadk2 [mitochondrial matrix]
(Mus musculus)
Nadk2 [mitochondrial matrix]
(Rattus norvegicus)
nadk2 [mitochondrial matrix]
(Xenopus tropicalis)
nadk-2 [mitochondrial matrix]
(Caenorhabditis elegans)
NADK2 [mitochondrial matrix]
(Bos taurus)
NADK2 [mitochondrial matrix]
(Canis familiaris)
NADK2 [mitochondrial matrix]
(Gallus gallus)
NADK2 [mitochondrial matrix]
(Plasmodium falciparum)
NADK2 [mitochondrial matrix]
(Sus scrofa)
Cross References
ENSEMBL
ENSG00000152620
,
ENST00000282512
,
ENSP00000282512
,
ENSP00000380499
,
ENST00000381937
,
ENSP00000371362
,
ENSP00000421029
,
ENST00000514504
,
ENST00000397338
OpenTargets
ENSG00000152620
IntEnz
2.7.1.23
GeneCards
NADK2
HPA
ENSG00000152620-NADK2
PRO
Q4G0N4
Pharos - Targets
Q4G0N4
Orphanet
NADK2
HMDB Protein
HMDBP11848
PDB
7R4L
,
7R4M
,
7R4J
,
7R4K
,
7N29
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