Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
GEMIN8 [nucleoplasm]
Stable Identifier
R-HSA-8932892
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Gem-associated protein 8, GEMI8_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Metabolism of non-coding RNA (Homo sapiens)
snRNP Assembly (Homo sapiens)
snRNP nuclear import and release (Homo sapiens)
SMN complex [nucleoplasm] (Homo sapiens)
GEMIN8 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NWZ8 GEMIN8
Gene Names
GEMIN8, FAM51A1
Chain
chain:1-242
Reference Genes
BioGPS Gene:54960 GEMIN8
COSMIC (genes):GEMIN8 GEMIN8
CTD Gene:54960 GEMIN8
dbSNP Gene:54960 GEMIN8
ENSEMBL:ENSG00000046647 GEMIN8
HGNC:26044 GEMIN8
KEGG:hsa:54960 GEMIN8
Monarch:54960 GEMIN8
NCBI Entrez Gene:54960 GEMIN8
OMIM:300962 GEMIN8
UCSC:Q9NWZ8 GEMIN8
Reference Transcript
RefSeq:XM_047442230.1 GEMIN8
RefSeq:XM_054327341.1 GEMIN8
RefSeq:NM_017856.3 GEMIN8
RefSeq:XM_017029617.1 GEMIN8
RefSeq:XM_017029618.1 GEMIN8
RefSeq:NM_001042479.2 GEMIN8
RefSeq:NM_001042480.2 GEMIN8
Other Identifiers
11729253_a_at
11735749_a_at
11735750_x_at
17109197
219252_PM_s_at
219252_s_at
222854_PM_s_at
222854_s_at
230758_PM_at
230758_at
2422230
2422235
3631161
4000268
4000270
4000271
4000272
4000274
4000278
4000279
4000280
4000281
4000282
4000283
4000284
4000285
4000286
4000287
4000288
4000289
4000290
52122_at
54960
56273_at
73757_at
8171373
A_24_P156576
GE55533
GE84987
GO:0000387
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006397
GO:0008380
GO:0016071
GO:0032797
GO:0034719
GO:0097504
HMNXSV003003247
HMNXSV003026585
HMNXSV003049523
Hs.123425.0.A1_3p_at
Hs.44423.0.S1_3p_a_at
ILMN_1748116
ILMN_2364088
PH_hs_0034660
TC0X000870.hg
g8923480_3p_a_at
Participates
as a component of
SMN complex [nucleoplasm] (Homo sapiens)
Other forms of this molecule
GEMIN8 [cytosol]
Inferred To
GEMIN8 [nucleoplasm]
(Bos taurus)
GEMIN8 [nucleoplasm]
(Gallus gallus)
GEMIN8 [nucleoplasm]
(Sus scrofa)
Gemin8 [nucleoplasm]
(Mus musculus)
Gemin8 [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of GEMIN8 [nucleoplasm]
(Canis familiaris)
Cross References
RefSeq
NP_001035944.1
,
XP_047298186.1
,
NP_060326.1
,
XP_054183316.1
,
XP_016885106.1
,
XP_016885107.1
,
NP_001035945.1
OpenTargets
ENSG00000046647
ENSEMBL
ENSP00000369895
,
ENSP00000505429
,
ENST00000680255
,
ENST00000398355
,
ENSG00000046647
,
ENSP00000505279
,
ENST00000477386
,
ENSP00000381398
,
ENST00000380523
HPA
ENSG00000046647-GEMIN8
GeneCards
GEMIN8
PRO
Q9NWZ8
Pharos - Targets
Q9NWZ8
PDB
7BBL
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62306 SNRPF
2
SNRPF [cytosol]
(R-HSA-191852)
SNRPF [nucleoplasm]
(R-HSA-71907)
0.725
5
UniProt:P62304 SNRPE
2
SNRPE [cytosol]
(R-HSA-191782)
SNRPE [nucleoplasm]
(R-HSA-71905)
0.643
5
UniProt:P14678 SNRPB
4
2xMe-SNRPB [cytosol]
(R-HSA-192218)
SNRPB [cytosol]
(R-HSA-191798)
Me2-R108,R112-SNRPB [nucleoplasm]
(R-HSA-192213)
SNRPB [nucleoplasm]
(R-HSA-71896)
0.527
3
UniProt:Q9Y3F4 STRAP
1
STRAP [cytosol]
(R-HSA-2127556)
0.527
3
UniProt:Q9H244 P2RY12
1
P2RY12 [plasma membrane]
(R-HSA-391959)
0.527
2
© 2025
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text