In response to oxidative stress, protein kinase C (PKC) phosphorylates NFE2L2 (NRF2) at residue serine 40 (Ser-40). It has been demonstrated that NRF2 phosphorylation at Ser-40 facilitates its nuclear translocation (Huang et al. 2002).
Nguyen, T, Pickett, CB, Huang, HC
protein kinase C activity of PRKCD [cytosol]
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