Synthesis of GABA by GAD2

Stable Identifier
R-HSA-888577
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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General
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GAD65 or GAD2 is concentrated in the nerve terminal region in the neurons and is involved in the synthesis of GABA which is used as a neurotransmitter.

Literature References
PubMed ID Title Journal Year
14691540 GAD2 on chromosome 10p12 is a candidate gene for human obesity

Boutin, P, Dina, C, Vasseur, F, Dubois, S, Corset, L, Séron, K, Bekris, L, Cabellon, J, Neve, B, Vasseur-Delannoy, V, Chikri, M, Charles, MA, Clement, K, Lernmark, A, Froguel, P

PLoS Biol 2003
Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
glutamate decarboxylase activity of PXLP-GAD dimers [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created