Synthesis of GABA by GAD2

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GAD65 or GAD2 is concentrated in the nerve terminal region in the neurons and is involved in the synthesis of GABA which is used as a neurotransmitter.

Literature References
PubMed ID Title Journal Year
14691540 GAD2 on chromosome 10p12 is a candidate gene for human obesity

Bekris, L, Neve, B, Dubois, S, Séron, K, Vasseur, F, Corset, L, Dina, C, Chikri, M, Clement, K, Vasseur-Delannoy, V, Lernmark, A, Boutin, P, Cabellon, J, Froguel, P, Charles, MA

PLoS Biol 2003
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Catalyst Activity

glutamate decarboxylase activity of PXLP-GAD dimers [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]

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Rhea
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