Based on studies in mice, RUNX2, presumably associated with CBFB, binds the evolutionarily conserved RUNX2 response elements in the promoter of the IHH (Indian hedgehog) gene (Yoshida et al. 2004).
Yoshida, CA, Yamamoto, H, Fujita, T, Furuichi, T, Ito, K, Inoue, K, Yamana, K, Zanma, A, Takada, K, Ito, Y, Komori, T
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