RUNX3 binds the NOTCH1 coactivator complex

Stable Identifier
R-HSA-8878220
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RUNX3 binds the NOTCH1 coactivator complex
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RUNX3 binds the NOTCH1 coactivator complex by directly interacting with the NOTCH1 intracellular domain fragment (NICD1) (Gao et al. 2010).
Literature References
PubMed ID Title Journal Year
19800882 RUNX3 directly interacts with intracellular domain of Notch1 and suppresses Notch signaling in hepatocellular carcinoma cells

Gao, J, Chen, Y, Du, R, Zhao, YQ, Xu, HL, Fan, DM, Liu, J, Wu, KC, Pan, YL, Zheng, GR, Xiong, YM

Exp. Cell Res. 2010
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Authored
Orlic-Milacic, M  (2016-12-13)
Reviewed
Ito, Y  (2017-01-31)
Chuang, LS  (2017-01-31)
Created
Orlic-Milacic, M  (2016-06-30)
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