Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
DENND1B [cytosol]
Stable Identifier
R-HSA-8877597
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
fullName evidence="20"DENN domain-containing protein 1B, DEN1B_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Homo sapiens)
DENND1A, DENND1B [cytosol] (Homo sapiens)
DENND1B [cytosol] (Homo sapiens)
DENND1s exchange GTP for GDP on RAB35 (Homo sapiens)
RAB35 GEFs [cytosol] (Homo sapiens)
DENND1B [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6P3S1 DENND1B
Gene Names
DENND1B, C1orf218, FAM31B
Chain
chain:1-775
Reference Genes
BioGPS Gene:163486 DENND1B
COSMIC (genes):DENND1B DENND1B
CTD Gene:163486 DENND1B
dbSNP Gene:163486 DENND1B
ENSEMBL:ENSG00000213047 DENND1B
ENSEMBL_homo_sapiens_GENE:ENSG00000213047.13 DENND1B
HGNC:28404 DENND1B
KEGG Gene (Homo sapiens):163486 DENND1B
Monarch:163486 DENND1B
NCBI Gene:163486 DENND1B
OMIM:613292 DENND1B
UCSC:Q6P3S1 DENND1B
Reference Transcript
RefSeq:NM_144977.4 DENND1B
RefSeq:NM_001195216.1 DENND1B
RefSeq:NM_001300858.1 DENND1B
RefSeq:NM_001195215.1 DENND1B
Other Identifiers
11740132_at
11750775_a_at
11759340_at
1552835_PM_at
1552835_at
163486
16697599
219696_PM_at
219696_at
228032_PM_s_at
228032_s_at
238787_PM_at
238787_at
2449686
2449687
2449688
2449690
2449692
2449694
2449695
2449696
2449697
2449698
2449701
2449703
2449705
2449706
2449708
2449712
2449713
2449715
2449716
2449720
2449723
2449725
2449728
2449731
2449733
2449734
2449736
2449738
2449739
2449741
2449752
2449756
2449757
2449760
2449761
2449762
2449763
2449769
46529_at
51849_at
58005_at
7923131
7923141
81393_at
87825_at
A_23_P201605
A_32_P204330
GE55350
GO:0002376
GO:0005085
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006897
GO:0008289
GO:0015031
GO:0016192
GO:0016607
GO:0023052
GO:0030136
GO:0031267
GO:0031410
GO:0032456
GO:0043226
GO:0043231
GO:0050776
GO:0050852
GO:0098772
GO:1901981
GO:2000553
HMNXSV003012504
HMNXSV003025316
HMNXSV003037618
Hs.125056.0.A1_3p_at
Hs.182278.7.S1_3p_s_at
Hs2.352164.1.S1_3p_at
ILMN_1763654
ILMN_1789436
ILMN_1862521
PH_hs_0005646
PH_hs_0023934
PH_hs_0032909
TC01003665.hg
TC01006025.hg
g9506654_3p_at
Participates
as a member of
RAB35 GEFs [cytosol] (Homo sapiens)
as a candidate of
DENND1A, DENND1B [cytosol] (Homo sapiens)
Other forms of this molecule
p-2S DENND1B [cytosol]
Inferred To
DENND1B [cytosol]
(Bos taurus)
DENND1B [cytosol]
(Canis familiaris)
DENND1B [cytosol]
(Dictyostelium discoideum)
DENND1B [cytosol]
(Gallus gallus)
DENND1B [cytosol]
(Sus scrofa)
CG30347 [cytosol]
(Drosophila melanogaster)
Dennd1b [cytosol]
(Mus musculus)
Dennd1b [cytosol]
(Rattus norvegicus)
rme-4 [cytosol]
(Caenorhabditis elegans)
dennd1b [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_659414.2
,
NP_001182145.1
,
NP_001287787.1
,
NP_001182144.1
OpenTargets
ENSG00000213047
GeneCards
Q6P3S1
HPA
ENSG00000213047-DENND1B
Ensembl
ENST00000620048
,
ENSP00000356366
,
ENSG00000213047
,
ENSP00000479816
,
ENST00000367396
,
ENST00000235453
,
ENSP00000235453
PRO
Q6P3S1
Pharos - Targets
Q6P3S1
PDB
3TW8
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text