Reactome | EEF2KMT [cytosol]

EEF2KMT [cytosol]

Stable Identifier

R-HSA-8876690

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

fullName evidence="8"Protein-lysine N-methyltransferase EEF2KMT ecNumber evidence="5"2.1.1.-/ecNumber, EF2KT_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P13682 ZNF35

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External Reference Information

External Reference

UniProt:Q96G04 EEF2KMT

Gene Names

EEF2KMT, FAM86A, SB153

Chain

chain:1-330

Reference Genes

BioGPS Gene:196483 EEF2KMT

COSMIC (genes):EEF2KMT EEF2KMT

CTD Gene:196483 EEF2KMT

dbSNP Gene:196483 EEF2KMT

ENSEMBL:ENSG00000118894 EEF2KMT

HGNC:32221 EEF2KMT

KEGG:hsa:196483 EEF2KMT

Monarch:196483 EEF2KMT

NCBI Gene:196483 EEF2KMT

OMIM:615263 EEF2KMT

UCSC:Q96G04 EEF2KMT

Reference Transcript

Other Identifiers

11758160_x_at

16823719

196483

222013_PM_x_at

222013_x_at

2683144

2683205

2695128

2695134

2758494

3084783

3084789

3124803

3339191

3359798

3359800

3359807

3678565

3678568

3678570

3678571

3678572

3678573

3678574

3678575

3678579

3678580

3678581

3678582

3678591

7999304

A_33_P3239084

GO:0003824

GO:0005515

GO:0005737

GO:0005829

GO:0006325

GO:0006338

GO:0008168

GO:0016279

GO:0016740

GO:0018023

GO:0032259

GO:0032991

GO:0042054

GO:0140096

HMNXSV003020632

HMNXSV003036082

ILMN_1780298

ILMN_2400250

PH_hs_0036808

TC16000842.hg

Inferred To

Eef2kmt [cytosol] (Rattus norvegicus)

eef2kmt [cytosol] (Danio rerio)

eef2kmt [cytosol] (Xenopus tropicalis)

EEF2KMT [cytosol] (Bos taurus)

EEF2KMT [cytosol] (Canis familiaris)

EEF2KMT [cytosol] (Gallus gallus)

EEF2KMT [cytosol] (Mus musculus)

EEF2KMT [cytosol] (Saccharomyces cerevisiae)

EEF2KMT [cytosol] (Schizosaccharomyces pombe)

EEF2KMT [cytosol] (Sus scrofa)

Dmel\CG7889 [cytosol] (Drosophila melanogaster)

Cross References

ENSEMBL

ENST00000427587, ENST00000458008, ENSP00000398502, ENSG00000118894, ENSP00000389710

OpenTargets

ENSG00000118894

GeneCards

EEF2KMT

HPA

ENSG00000118894-EEF2KMT

PRO

Q96G04

Pharos - Targets

Q96G04

GlyGen

Q96G04

PDB

8FZB

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NRG1 PRDC1			0.83	8
UniProt:Q86T90 K1328			0.556	3
UniProt:P13682 ZNF35			0.556	3
UniProt:P31321 PRKAR1B	2	PRKAR1B [cytosol] (R-HSA-57838) PRKAR1B [ciliary base] (R-HSA-5610409)	0.556	3
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.556	3
UniProt:O14771 ZNF213	1	ZNF213 [nucleoplasm] (R-HSA-1027351)	0.556	3
UniProt:P51843 NR0B1			0.556	3
UniProt:P00492 HPRT1	4	HPRT1 [cytosol] (R-HSA-56639) HPRT1 G140D [cytosol] (R-HSA-9734264) HPRT1 G70E [cytosol] (R-HSA-9734286) HPRT1 D194N [cytosol] (R-HSA-9734269)	0.556	3
UniProt:Q6ZNG0 ZNF620	1	ZNF620 [nucleoplasm] (R-HSA-2127603)	0.556	3
UniProt:Q15645 PCH2			0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:Q13099 IFT88	8	PolyUb-Misfolded IFT88 [lysosomal lumen] (R-HSA-9660026) PolyUb-Misfolded IFT88 [cytosol] (R-HSA-9641125) Ub-Misfolded IFT88 [cytosol] (R-HSA-9641114) Misfolded IFT88 [cytosol] (R-HSA-9640115) Misfolded IFT88 [cilium] (R-HSA-9640106) IFT88 [cilium] (R-HSA-5610385) PolyUb-Misfolded IFT88 [late endosome lumen] (R-HSA-9660031) IFT88 [ciliary tip] (R-HSA-5625371)	0.556	3
UniProt:O15382 BCAT2	1	PXLP-BCAT2 [mitochondrial matrix] (R-HSA-70703)	0.527	3

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