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InlA:CDH1:CTNNB1:CTNND1 [plasma membrane]
Stable Identifier
R-HSA-8876504
Type
Complex
Species
Homo sapiens
Related Species
Listeria monocytogenes
Compartment
plasma membrane
Synonyms
Internalin A:E-cadherin:beta-catenin:p120 catenin
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Listeria monocytogenes entry into host cells (Homo sapiens)
InlA-mediated entry of Listeria monocytogenes into host cells (Homo sapiens)
InlA binds CDH1 (Homo sapiens)
InlA:CDH1:CTNNB1:CTNND1 [plasma membrane] (Homo sapiens)
SRC autophosphorylation is positively regulated by InlA-bound CDH1 (Homo sapiens)
InlA:CDH1:CTNNB1:CTNND1 [plasma membrane] (Homo sapiens)
SRC phosphorylates InlA-bound CDH1 and CTNNB1 (Homo sapiens)
InlA:CDH1:CTNNB1:CTNND1 [plasma membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
8601315
E-cadherin is the receptor for internalin, a surface protein required for entry of L. monocytogenes into epithelial cells
Cossart, P
,
Mege R-M, R-M
,
Ohayon, H
,
Gounon, P
,
Mengaud, J
Cell
1996
Participants
components
CDH1:CTNNB1:CTNND1 [plasma membrane]
(Homo sapiens)
InlA [peptidoglycan-based cell wall]
(Listeria monocytogenes)
Participates
as an output of
InlA binds CDH1 (Homo sapiens)
as an input of
SRC phosphorylates InlA-bound CDH1 and CTNNB1 (Homo sapiens)
This entity regulates
Positively
SRC autophosphorylation is positively regulated by InlA-bound CDH1
(Homo sapiens)
Disease
Name
Identifier
Synonyms
listeriosis
DOID:11573
Infection by Listeria monocytogenes, Infection due to Listeria monocytogenes, Listeria infection, Listeriosis
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