Internalin (InlA), a cell wall protein of Listeria monocytogenes, binds to the E-cadherin (CDH1) complex at the plasma membrane of the host cell, triggering bacterial entry (Mengaud et al. 1996). The first extracellular domain (EC1) of CDH1 is involved in InlA binding, with proline residue P16 being critical for the interaction (Lecuit et al. 1999).
Gottardi, C, Gumbiner, B, Cossart, P, Lecuit, M, Dramsi, S, Fedor-Chaiken, M
Cossart, P, Mege R-M, R-M, Ohayon, H, Gounon, P, Mengaud, J
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