GGC-RAB12 [recycling endosome membrane]

Stable Identifier
R-HSA-8876449
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
recycling endosome membrane
Synonyms
Ras-related protein Rab-12, RAB12_HUMAN
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:Q6IQ22 RAB12
Gene Names
RAB12
Chain
chain:1-244
Reference Genes
BioGPS Gene:201475 RAB12
COSMIC (genes):RAB12 RAB12
CTD Gene:201475 RAB12
dbSNP Gene:201475 RAB12
ENSEMBL:ENSG00000206418 RAB12
HGNC:31332 RAB12
Monarch:201475 RAB12
NCBI Gene:201475 RAB12
OMIM:616448 RAB12
UCSC:Q6IQ22 RAB12
Reference Transcript
Participates
as a component of
Other forms of this molecule
GGC-RAB12 [cytosol]
RAB12 [cytosol]
Inferred To
Homologues of GGC-RAB12 [recycling endosome membrane] (Caenorhabditis elegans)
Homologues of GGC-RAB12 [recycling endosome membrane] (Dictyostelium discoideum)
Homologues of GGC-RAB12 [recycling endosome membrane] (Schizosaccharomyces pombe)
rabr-1 [recycling endosome membrane] (Caenorhabditis elegans)
RAB12 [recycling endosome membrane] (Bos taurus)
RAB12 [recycling endosome membrane] (Canis familiaris)
RAB12 [recycling endosome membrane] (Sus scrofa)
Rab8 [recycling endosome membrane] (Drosophila melanogaster)
rab-8 [recycling endosome membrane] (Caenorhabditis elegans)
GGC-RAB12 [recycling endosome membrane] (Dictyostelium discoideum)
GGC-RAB12 [recycling endosome membrane] (Gallus gallus)
GGC-RAB12 [recycling endosome membrane] (Mus musculus)
GGC-RAB12 [recycling endosome membrane] (Rattus norvegicus)
GGC-RAB12 [recycling endosome membrane] (Saccharomyces cerevisiae)
GGC-RAB12 [recycling endosome membrane] (Schizosaccharomyces pombe)
rab12 [recycling endosome membrane] (Danio rerio)
rab12 [recycling endosome membrane] (Xenopus tropicalis)
Modified Residues
Name
S-geranylgeranyl-L-cysteine at 243
Coordinate
243
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Name
S-geranylgeranyl-L-cysteine at 244
Coordinate
244
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Cross References
OpenTargets
PRO
Pharos - Targets
PDB
Interactors (2)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P24386 CHM  1 0.527 2
 UniProt:Q5S007 LRRK2  1 0.499 2
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