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GGC-RAB12 [recycling endosome membrane]
Stable Identifier
R-HSA-8876449
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
recycling endosome membrane
Synonyms
Ras-related protein Rab-12, RAB12_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
DENND3 exchanges GTP for GDP on RAB12 (Homo sapiens)
GGC-RAB12:GTP [recycling endosome membrane] (Homo sapiens)
GGC-RAB12 [recycling endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6IQ22 RAB12
Gene Names
RAB12
Chain
chain:1-244
Reference Genes
BioGPS Gene:201475 RAB12
COSMIC (genes):RAB12 RAB12
CTD Gene:201475 RAB12
dbSNP Gene:201475 RAB12
ENSEMBL:ENSG00000206418 RAB12
HGNC:31332 RAB12
KEGG Gene (Homo sapiens):201475 RAB12
Monarch:201475 RAB12
NCBI Gene:201475 RAB12
OMIM:616448 RAB12
UCSC:Q6IQ22 RAB12
Reference Transcript
RefSeq:NM_001025300.2 RAB12
Other Identifiers
0004780037
11735606_x_at
11754674_a_at
16850797
201475
235059_at
239891_x_at
3777894
3777895
3777896
3777898
3777900
3777901
3777902
3777904
3777906
3777907
3777908
43225_i_at
43226_r_at
50154_at
8020029
A_23_P119023
A_24_P53353
A_33_P3391211
GE794702
GO:0000139
GO:0000166
GO:0002376
GO:0003674
GO:0003924
GO:0005515
GO:0005525
GO:0005575
GO:0005622
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005776
GO:0005794
GO:0005829
GO:0005886
GO:0006810
GO:0006904
GO:0006914
GO:0006950
GO:0007034
GO:0007165
GO:0008021
GO:0008150
GO:0008333
GO:0009056
GO:0009306
GO:0015031
GO:0016020
GO:0016192
GO:0016239
GO:0017157
GO:0019003
GO:0031410
GO:0032482
GO:0032593
GO:0032869
GO:0043167
GO:0043226
GO:0044257
GO:0045335
GO:0055037
GO:0055038
GO:0071346
GO:0072659
Hs.175870.0.A1_3p_at
Hs.175870.0.A1_3p_x_at
Hs.29739.0.A1_3p_at
PH_hs_0002570
TC18000039.hg
Participant Of
hasComponent
GGC-RAB12:GTP [recycling endosome membrane]
Other forms of this molecule
GGC-RAB12 [cytosol]
RAB12 [cytosol]
Inferred To
Homologues of GGC-RAB12 [recycling endosome membrane] (Caenorhabditis elegans)
Homologues of GGC-RAB12 [recycling endosome membrane] (Dictyostelium discoideum)
Homologues of GGC-RAB12 [recycling endosome membrane] (Drosophila melanogaster)
Homologues of GGC-RAB12 [recycling endosome membrane] (Schizosaccharomyces pombe)
Rab9Fa [recycling endosome membrane] (Drosophila melanogaster)
SEC4 [recycling endosome membrane] (Saccharomyces cerevisiae)
rab8B [recycling endosome membrane] (Dictyostelium discoideum)
ypt4 [recycling endosome membrane] (Schizosaccharomyces pombe)
RAB12 [recycling endosome membrane] (Bos taurus)
RAB12 [recycling endosome membrane] (Gallus gallus)
RAB12 [recycling endosome membrane] (Sus scrofa)
Rab9Db [recycling endosome membrane] (Drosophila melanogaster)
Dmel\CG15399 [recycling endosome membrane] (Drosophila melanogaster)
GGC-RAB12 [recycling endosome membrane] (Caenorhabditis elegans)
GGC-RAB12 [recycling endosome membrane] (Canis familiaris)
RabX2 [recycling endosome membrane] (Drosophila melanogaster)
rab8A [recycling endosome membrane] (Dictyostelium discoideum)
rab12 [recycling endosome membrane] (Danio rerio)
rab12 [recycling endosome membrane] (Xenopus tropicalis)
ypt2 [recycling endosome membrane] (Schizosaccharomyces pombe)
Rab9E [recycling endosome membrane] (Drosophila melanogaster)
rab-10 [recycling endosome membrane] (Caenorhabditis elegans)
rabV [recycling endosome membrane] (Dictyostelium discoideum)
Rab12 [recycling endosome membrane] (Mus musculus)
Rab12 [recycling endosome membrane] (Rattus norvegicus)
Rab9Fb [recycling endosome membrane] (Drosophila melanogaster)
Rab10 [recycling endosome membrane] (Drosophila melanogaster)
Rab9D [recycling endosome membrane] (Drosophila melanogaster)
rabZ [recycling endosome membrane] (Dictyostelium discoideum)
RabX4 [recycling endosome membrane] (Drosophila melanogaster)
Modified Residues
Name
S-geranylgeranyl-L-cysteine at 243
Coordinate
243
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Name
S-geranylgeranyl-L-cysteine at 244
Coordinate
244
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Cross References
RefSeq
NP_001020471.2
OpenTargets
ENSG00000206418
GeneCards
Q6IQ22
HPA
ENSG00000206418-RAB12
Ensembl
ENSP00000331748
,
ENSG00000206418
,
ENST00000329286
PRO
Q6IQ22
PDB
2IL1
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.499
2
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