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HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane]
Stable Identifier
R-HSA-8876374
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by MET (Homo sapiens)
Negative regulation of MET activity (Homo sapiens)
CBL monoubiquitinates activated MET (Homo sapiens)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Homo sapiens)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane] (Homo sapiens)
CBL recruits CIN85:endophilin to ubiquitinated MET (Homo sapiens)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Homo sapiens)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane] (Homo sapiens)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin [plasma membrane] (Homo sapiens)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Homo sapiens)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane] (Homo sapiens)
EPS15 and HGS bind ubiquitinated MET (Homo sapiens)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin,(MET:Ub-LRIG1) [plasma membrane] (Homo sapiens)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin [plasma membrane] (Homo sapiens)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Homo sapiens)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane] (Homo sapiens)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin:EPS15:HGS:STAM,(MET:Ub-LRIG1:EPS15:HGS:STAM) [plasma membrane] (Homo sapiens)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin,(MET:Ub-LRIG1) [plasma membrane] (Homo sapiens)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin [plasma membrane] (Homo sapiens)
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Homo sapiens)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane] (Homo sapiens)
Participants
components
HGF:MonoUb-K,p-Y1003,4Y-MET dimer [plasma membrane]
(Homo sapiens)
p-Y-CBL [cytosol]
(Homo sapiens)
Participates
as a candidate of
HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Homo sapiens)
Inferred To
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane]
(Bos taurus)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane]
(Caenorhabditis elegans)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane]
(Canis familiaris)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane]
(Gallus gallus)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane]
(Mus musculus)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane]
(Rattus norvegicus)
HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane]
(Sus scrofa)
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