SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol

Stable Identifier
R-HSA-8876283
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The sodium/glucose cotransporter 5 (SLC5A10, sodium glucose cotransporter 5, SGLT5) is a plasma membrane-bound transport protein that possesses high capacity to transport mannose (Man) and fructose (Fru) into cells (Grempler et al. 2012). SLC5A10 is exclusively expressed in the kidney and is also able to transport glucose, alpha-methyl-D-glucose (AMG) and galactose, although to a much lower extent than Man and Fru.

Literature References
PubMed ID Title Journal Year
22212718 Functional characterisation of human SGLT-5 as a novel kidney-specific sodium-dependent sugar transporter

Grempler, R, Augustin, R, Froehner, S, Hildebrandt, T, Simon, E, Mark, M, Eickelmann, P

FEBS Lett. 2012
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Catalyst Activity

solute:sodium symporter activity of SLC5A10 [plasma membrane]

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