The STAT3 transcription factor may bind, directly and indirectly, to activated MET. Direct binding of STAT3 involves phosphorylated tyrosine residue Y1356 of MET. Indirect binding of STAT3 to activated MET involves GAB1, but this interaction has not been studied in detail (Schaper et al. 1997, Boccaccio et al. 1998).
Bardelli, A, Comoglio, PM, Battistini, C, Tamagnone, L, Boccaccio, C, Andò, M, Michieli, P
Schaper, F, Gatsios, P, Castell, J, Gómez-Lechon, MJ, Birchmeier, W, Siewert, E, Heinrich, PC, Sachs, M
© 2022 Reactome