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GGC-RAB4A [recycling endosome membrane]
Stable Identifier
R-HSA-8875666
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
recycling endosome membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by MET (Homo sapiens)
MET receptor recycling (Homo sapiens)
RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Homo sapiens)
GGC-RAB4:GTP [recycling endosome membrane] (Homo sapiens)
GGC-RAB4 [recycling endosome membrane] (Homo sapiens)
GGC-RAB4A [recycling endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P20338 RAB4A
Gene Names
RAB4A, RAB4
Chain
chain:1-218
Reference Genes
BioGPS Gene:5867 RAB4A
COSMIC (genes):RAB4A RAB4A
CTD Gene:5867 RAB4A
dbSNP Gene:5867 RAB4A
ENSEMBL:ENSG00000168118 RAB4A
ENSEMBL_homo_sapiens_GENE:ENSG00000168118.12 RAB4A
HGNC:9781 RAB4A
KEGG Gene (Homo sapiens):5867 RAB4A
Monarch:5867 RAB4A
NCBI Gene:5867 RAB4A
OMIM:179511 RAB4A
UCSC:P20338 RAB4A
Reference Transcript
RefSeq:NM_004578.3 RAB4A
RefSeq:NM_001271998.1 RAB4A
Other Identifiers
11721301_a_at
11743887_s_at
11758844_at
16678536
1685_at
1686_g_at
203581_PM_at
203581_at
203582_PM_s_at
203582_s_at
206272_PM_at
206272_at
2384563
2384564
2384565
2384567
2384570
2384576
2384577
2384578
2384579
2384580
2384581
2384583
2384584
2384585
2384586
2384587
2384588
2384589
2384590
39244_at
5867
621_at
7910398
A_14_P119800
A_14_P125512
A_23_P217938
A_23_P369919
A_24_P122682
GE57900
GE80410
GO:0000166
GO:0002376
GO:0003824
GO:0003924
GO:0003925
GO:0005515
GO:0005525
GO:0005576
GO:0005615
GO:0005737
GO:0005768
GO:0007264
GO:0015031
GO:0016020
GO:0016192
GO:0016787
GO:0019003
GO:0019882
GO:0023052
GO:0030100
GO:0030659
GO:0031410
GO:0031901
GO:0031982
GO:0032482
GO:0032593
GO:0043226
GO:0048471
GO:0055038
GO:0070062
GO:0098772
GO:0098837
HMNXSV003016611
HMNXSV003039554
ILMN_1677824
ILMN_1718832
M28211_at
PH_hs_0026610
TC01001900.hg
TC01005092.hg
X82554_rna1_at
g12803248_3p_at
g4759001_3p_a_at
g5730062_3p_at
Participates
as a member of
GGC-RAB4 [recycling endosome membrane] (Homo sapiens)
Other forms of this molecule
GGC-RAB4A [cytoplasmic vesicle membrane]
GGC-RAB4A [cytosol]
RAB4A [cytosol]
RAB4A [early endosome membrane]
Inferred To
GGC-RAB4A [recycling endosome membrane]
(Bos taurus)
GGC-RAB4A [recycling endosome membrane]
(Gallus gallus)
GGC-RAB4A [recycling endosome membrane]
(Mus musculus)
GGC-RAB4A [recycling endosome membrane]
(Rattus norvegicus)
RAB4A [recycling endosome membrane]
(Canis familiaris)
RAB4A [recycling endosome membrane]
(Sus scrofa)
Modified Residues
Name
S-geranylgeranyl-L-cysteine at 216
Coordinate
216
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Name
S-geranylgeranyl-L-cysteine at 218
Coordinate
218
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Cross References
RefSeq
NP_004569.2
,
NP_001258927.1
OpenTargets
ENSG00000168118
GeneCards
P20338
HPA
ENSG00000168118-RAB4A
Ensembl
ENST00000366690
,
ENSP00000355651
,
ENSG00000168118
PRO
P20338
Pharos - Targets
P20338
PDB
2BMD
,
1Z0K
,
2BME
,
1YU9
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O00471 EXOC5
2
EXOC5 [cytosol]
(R-HSA-265045)
EXOC5 [cytosol]
(R-HSA-5623383)
0.718
6
UniProt:Q9H1K0 RBSN
1
ZFYVE20 [endosome membrane]
(R-HSA-188000)
0.659
4
GTP [ChEBI:15996]
7
GTP [cilium]
(R-ALL-5617813)
GTP [early endosome membrane]
(R-ALL-2130170)
GTP [lysosomal membrane]
(R-ALL-2213216)
GTP [platelet dense granule lumen]
(R-ALL-114625)
GTP [cytoplasmic vesicle membrane]
(R-ALL-1996291)
GTP [ER to Golgi transport vesicle membrane]
(R-ALL-983318)
GTP [Golgi membrane]
(R-ALL-1806221)
0.623
3
UniProt:Q96JA1 LRIG1
2
Ub-LRIG1 [plasma membrane]
(R-HSA-8875434)
LRIG1 [plasma membrane]
(R-HSA-197745)
0.527
2
UniProt:Q92597 NDRG1
1
NDRG1 [cytosol]
(R-HSA-5628834)
0.463
2
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