Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
6xHC-CMC4 [mitochondrial intermembrane space]
Stable Identifier
R-HSA-8874861
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial intermembrane space
Synonyms
Cx9C motif-containing protein 4, CMC4_HUMAN
Locations in the PathwayBrowser
Expand all
Protein localization (Homo sapiens)
Mitochondrial protein import (Homo sapiens)
MIA40:ERV1 (CHCHD4:GFER) oxidizes cysteine residues to cystine disulfide bonds (Homo sapiens)
Products of MIA40:ERV1 [mitochondrial intermembrane space] (Homo sapiens)
6xHC-CMC4 [mitochondrial intermembrane space] (Homo sapiens)
External Reference Information
External Reference
UniProt:P56277 CMC4
Gene Names
CMC4, C6.1B, MTCP1, MTCP1NB
Chain
chain:1-68
Reference Genes
BioGPS Gene:100272147 CMC4
COSMIC (genes):CMC4 CMC4
CTD Gene:100272147 CMC4
dbSNP Gene:100272147 CMC4
ENSEMBL:ENSG00000182712 CMC4
ENSEMBL_homo_sapiens_GENE:ENSG00000182712.16 CMC4
HGNC:35428 CMC4
KEGG Gene (Homo sapiens):100272147 CMC4
Monarch:100272147 CMC4
NCBI Gene:100272147 CMC4
OMIM:301088 CMC4
UCSC:P56277 CMC4
Reference Transcript
RefSeq:NM_001018024.2 CMC4
Other Identifiers
100272147
11717654_a_at
17115765
205106_PM_at
205106_at
210212_PM_x_at
210212_x_at
216862_PM_s_at
216862_s_at
35686_s_at
35687_at
35688_g_at
4027710
4027711
4027712
4027714
4027715
4027716
4027717
4027718
4027719
4027720
4027721
4027722
4027726
8176219
A_23_P11295
A_24_P324520
GE60375
GO:0005739
GO:0005758
GO:0043226
HMNXSV003037766
ILMN_1814230
PH_hs_0027547
g7657348_3p_a_at
Participates
as a candidate of
Products of MIA40:ERV1 [mitochondrial intermembrane space] (Homo sapiens)
Other forms of this molecule
CMC4 [mitochondrial intermembrane space]
Inferred From
4xHC-CMC4 [mitochondrial intermembrane space]
(Saccharomyces cerevisiae)
Modified Residues
Name
Intra-chain Crosslink via L-cystine (cross-link) at 7 and 38
Coordinate
7
PsiMod Name
L-cystine (cross-link)
PsiMod Definition
A protein modification that effectively cross-links two L-cysteine residues to form L-cystine.
Name
Intra-chain Crosslink via L-cystine (cross-link) at 17 and 28
Coordinate
17
PsiMod Name
L-cystine (cross-link)
PsiMod Definition
A protein modification that effectively cross-links two L-cysteine residues to form L-cystine.
Name
Intra-chain Crosslink via L-cystine (cross-link) at 39 and 50
Coordinate
39
PsiMod Name
L-cystine (cross-link)
PsiMod Definition
A protein modification that effectively cross-links two L-cysteine residues to form L-cystine.
Cross References
RefSeq
NP_001018024.1
OpenTargets
ENSG00000182712
HPA
ENSG00000182712-CMC4
GeneCards
P56277
Ensembl
ENST00000369484
,
ENST00000369479
,
ENSP00000358496
,
ENSP00000358491
,
ENSG00000182712
PRO
P56277
Pharos - Targets
P56277
PDB
2HP8
,
1EI0
,
1HP8
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text