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HGF:p-Y1003,4Y-MET dimer [plasma membrane]
Stable Identifier
R-HSA-8874694
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
HGF:p-Y1003,Y1234,Y1235,Y1349,Y1356-MET dimer
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by MET (Homo sapiens)
Negative regulation of MET activity (Homo sapiens)
CBL binds MET (Homo sapiens)
HGF:p-4Y-MET dimer,(HGF:p-Y1003,4Y-METdimer) [plasma membrane] (Homo sapiens)
HGF:p-Y1003,4Y-MET dimer [plasma membrane] (Homo sapiens)
CBL monoubiquitinates activated MET (Homo sapiens)
HGF:p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Homo sapiens)
HGF:p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane] (Homo sapiens)
HGF:p-Y1003,4Y-MET dimer [plasma membrane] (Homo sapiens)
MET phosphorylates CBL (Homo sapiens)
HGF:p-4Y-MET dimer,(HGF:p-Y1003,4Y-METdimer) [plasma membrane] (Homo sapiens)
HGF:p-Y1003,4Y-MET dimer [plasma membrane] (Homo sapiens)
HGF:p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:p-Y1003,4Y-MET dimer:p-Y-CBL) [plasma membrane] (Homo sapiens)
HGF:p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane] (Homo sapiens)
HGF:p-Y1003,4Y-MET dimer [plasma membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
15167892
Crystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptor
Kirchhofer, D
,
Wiesmann, C
,
Stamos, J
,
Yao, X
,
Lazarus, RA
EMBO J.
2004
Participants
components
x 2
HGF dimer:p-Y1003,4Y-MET [plasma membrane]
(Homo sapiens)
Participates
as a component of
HGF:p-Y1003,4Y-MET dimer:p-Y-CBL [plasma membrane] (Homo sapiens)
as a candidate of
HGF:p-4Y-MET dimer,(HGF:p-Y1003,4Y-METdimer) [plasma membrane] (Homo sapiens)
Inferred To
HGF:p-Y1003,4Y-MET dimer [plasma membrane]
(Bos taurus)
HGF:p-Y1003,4Y-MET dimer [plasma membrane]
(Caenorhabditis elegans)
HGF:p-Y1003,4Y-MET dimer [plasma membrane]
(Canis familiaris)
HGF:p-Y1003,4Y-MET dimer [plasma membrane]
(Gallus gallus)
HGF:p-Y1003,4Y-MET dimer [plasma membrane]
(Mus musculus)
HGF:p-Y1003,4Y-MET dimer [plasma membrane]
(Rattus norvegicus)
HGF:p-Y1003,4Y-MET dimer [plasma membrane]
(Sus scrofa)
HGF:p-Y1003,4Y-MET dimer [plasma membrane]
(Xenopus tropicalis)
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