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ATF6B(441-703) [Golgi membrane]
Stable Identifier
R-HSA-8874147
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
Cyclic AMP-dependent transcription factor ATF-6 beta, ATF6B_HUMAN
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Unfolded Protein Response (UPR) (Homo sapiens)
ATF6B (ATF6-beta) activates chaperones (Homo sapiens)
MBTPS1 (S1P) cleaves ATF6B (ATF6-beta) (Homo sapiens)
ATF6B(441-703) [Golgi membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
19693772
N-glycosylation of ATF6beta is essential for its proteolytic cleavage and transcriptional repressor function to ATF6alpha
Yang, M
,
Li, VE
,
Shen, Z
,
Wang, H
,
Xu, Y
,
Guan, D
J. Cell. Biochem.
2009
External Reference Information
External Reference
UniProt:Q99941 ATF6B
Gene Names
ATF6B, CREBL1, G13
Chain
initiator methionine:, chain:2-703, chain:2-
Reference Genes
BioGPS Gene:1388 ATF6B
COSMIC (genes):ATF6B ATF6B
CTD Gene:1388 ATF6B
dbSNP Gene:1388 ATF6B
ENSEMBL:ENSG00000213676 ATF6B
ENSEMBL_homo_sapiens_GENE:ENSG00000168468.12 ATF6B
ENSEMBL_homo_sapiens_GENE:ENSG00000213676.13 ATF6B
ENSEMBL_homo_sapiens_GENE:ENSG00000228628.8 ATF6B
ENSEMBL_homo_sapiens_GENE:ENSG00000234539.9 ATF6B
HGNC:2349 ATF6B
KEGG Gene (Homo sapiens):1388 ATF6B
Monarch:1388 ATF6B
NCBI Gene:1388 ATF6B
OMIM:600984 ATF6B
UCSC:Q99941 ATF6B
Reference Transcript
RefSeq:NM_004381.4 ATF6B
RefSeq:NM_001136153.1 ATF6B
Other Identifiers
11720962_x_at
11747854_x_at
11750605_a_at
1388
1554487_3p_a_at
1554487_PM_a_at
1554487_a_at
1565242_PM_at
1565242_at
17017697
203168_PM_at
203168_at
211611_PM_s_at
211611_s_at
216208_PM_s_at
216208_s_at
2949727
2949728
2949729
2949730
2949732
2949733
2949734
2949735
2949736
2949737
2949739
2949741
2949742
2949743
2949747
2949748
2949750
2949752
2949753
2949754
2949755
2949756
2949758
2949759
36000_at
8125295
8178727
87202_f_at
A_23_P59163
A_24_P419109
A_24_P911362
A_33_P3305458
GE60199
GO:0000139
GO:0000785
GO:0000976
GO:0000978
GO:0000981
GO:0001228
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0006986
GO:0007165
GO:0016020
GO:0023052
GO:0030968
GO:0032993
GO:0034976
GO:0036500
GO:0043226
GO:0045944
GO:0090575
GO:0140110
GO:1903892
GO:1990837
HMNXSV003000919
HMNXSV003035706
Hs.42853.1.S1_3p_s_at
Hs2.384513.1.S1_3p_at
ILMN_1814313
PH_hs_0031185
TC06003597.hg
TC06004121.hg
TC6_cox_hap2000261.hg
TC6_dbb_hap3000238.hg
TC6_mcf_hap5000199.hg
U31903_s_at
U52700_at
g1703481_3p_s_at
g4758057_3p_at
Participates
as an output of
MBTPS1 (S1P) cleaves ATF6B (ATF6-beta) (Homo sapiens)
Other forms of this molecule
ATF6B(2-398) [nucleoplasm]
ATF6B(399-440) [Golgi membrane]
ATF6B(2-398) [cytosol]
ATF6B(2-440) [Golgi membrane]
ATF6B [Golgi membrane]
ATF6B [endoplasmic reticulum membrane]
Inferred To
ATF6B(441-703) [Golgi membrane]
(Sus scrofa)
Atf6 [Golgi membrane]
(Drosophila melanogaster)
Atf6b [Golgi membrane]
(Mus musculus)
Atf6b [Golgi membrane]
(Rattus norvegicus)
atf-6 [Golgi membrane]
(Caenorhabditis elegans)
ATF6B [Golgi membrane]
(Bos taurus)
ATF6B [Golgi membrane]
(Canis familiaris)
bzpL [Golgi membrane]
(Dictyostelium discoideum)
Modified Residues
Name
glycosylated residue at 476
Coordinate
476
PsiMod Name
glycosylated residue
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with an carbohydrate-like group through a glycosidic bond.
Name
glycosylated residue at 505
Coordinate
505
PsiMod Name
glycosylated residue
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with an carbohydrate-like group through a glycosidic bond.
Name
glycosylated residue at 610
Coordinate
610
PsiMod Name
glycosylated residue
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with an carbohydrate-like group through a glycosidic bond.
Name
glycosylated residue at 627
Coordinate
627
PsiMod Name
glycosylated residue
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with an carbohydrate-like group through a glycosidic bond.
Name
glycosylated residue at 676
Coordinate
676
PsiMod Name
glycosylated residue
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with an carbohydrate-like group through a glycosidic bond.
Cross References
RefSeq
NP_004372.3
,
NP_001129625.1
OpenTargets
ENSG00000213676
GeneCards
Q99941
HPA
ENSG00000213676-ATF6B
Ensembl
ENST00000439240
,
ENST00000375201
,
ENST00000375203
,
ENSP00000293709
,
ENSP00000391131
,
ENSG00000228628
,
ENSP00000364349
,
ENSG00000213676
,
ENST00000293709
,
ENST00000435768
,
ENSP00000372642
,
ENST00000425571
,
ENSG00000234539
,
ENSP00000399764
,
ENSG00000168468
,
ENSP00000364347
,
ENSP00000404725
,
ENSP00000404814
,
ENST00000427136
,
ENST00000383156
PRO
Q99941
Pharos - Targets
Q99941
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P27958-PRO_0000037575
0.543
5
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