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CREB3 [Golgi membrane]
Stable Identifier
R-HSA-8874123
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
Cyclic AMP-responsive element-binding protein 3, CREB3_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q53HI1 UNC50
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Unfolded Protein Response (UPR) (Homo sapiens)
CREB3 factors activate genes (Homo sapiens)
CREB3 translocates from the endoplasmic reticulum membrane to the Golgi membrane (Homo sapiens)
CREB3 [Golgi membrane] (Homo sapiens)
MBTPS1 (S1P) cleaves CREB3 (Homo sapiens)
CREB3 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43889 CREB3
Gene Names
CREB3, LZIP
Chain
chain:1-371, chain:1-
Reference Genes
BioGPS Gene:10488 CREB3
COSMIC (genes):CREB3 CREB3
CTD Gene:10488 CREB3
dbSNP Gene:10488 CREB3
ENSEMBL:ENSG00000107175 CREB3
ENSEMBL_homo_sapiens_GENE:ENSG00000107175.12 CREB3
HGNC:2347 CREB3
KEGG Gene (Homo sapiens):10488 CREB3
Monarch:10488 CREB3
NCBI Gene:10488 CREB3
OMIM:606443 CREB3
UCSC:O43889 CREB3
Reference Transcript
RefSeq:NM_006368.4 CREB3
Other Identifiers
10488
11723024_a_at
17084736
209432_PM_s_at
209432_s_at
3168106
3168107
3168108
3168110
3168111
3168112
3168114
3168115
3168117
3168118
3168119
3168120
40849_s_at
8155096
AF009368_at
A_14_P200251
GE59521
GO:0000139
GO:0000785
GO:0000977
GO:0000978
GO:0000981
GO:0001221
GO:0001228
GO:0001558
GO:0002230
GO:0002376
GO:0003677
GO:0003682
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0006935
GO:0006986
GO:0008140
GO:0012501
GO:0016020
GO:0016604
GO:0019043
GO:0019046
GO:0023052
GO:0030335
GO:0030968
GO:0031726
GO:0042127
GO:0042802
GO:0042803
GO:0042981
GO:0042994
GO:0043025
GO:0043226
GO:0045786
GO:0045893
GO:0045944
GO:0046983
GO:0048870
GO:0050930
GO:0051928
GO:0090026
GO:0090575
GO:0098542
GO:0140110
GO:0140467
GO:1902236
GO:1990837
HMNXSV003030571
ILMN_1703072
PH_hs_0014926
TC09000192.hg
g2599559_3p_a_at
Participates
as an output of
CREB3 translocates from the endoplasmic reticulum membrane to the Golgi membrane (Homo sapiens)
as an input of
MBTPS1 (S1P) cleaves CREB3 (Homo sapiens)
Other forms of this molecule
CREB3(1-256) [nucleoplasm]
CREB3(1-256) [cytosol]
CREB3(1-291) [Golgi membrane]
CREB3(257-291) [Golgi membrane]
CREB3(292-371) [Golgi membrane]
CREB3 [endoplasmic reticulum membrane]
Inferred To
let-607 [Golgi membrane]
(Caenorhabditis elegans)
Creb3 [Golgi membrane]
(Mus musculus)
Creb3 [Golgi membrane]
(Rattus norvegicus)
CREB3 [Golgi membrane]
(Bos taurus)
CREB3 [Golgi membrane]
(Canis familiaris)
CREB3 [Golgi membrane]
(Gallus gallus)
CREB3 [Golgi membrane]
(Sus scrofa)
Cross References
RefSeq
NP_006359.3
OpenTargets
ENSG00000107175
HPA
ENSG00000107175-CREB3
GeneCards
O43889
Ensembl
ENSP00000342136
,
ENSG00000107175
,
ENST00000353704
PRO
O43889
Pharos - Targets
O43889
HMDB Protein
HMDBP08122
Interactors (27)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P51610 HCFC1
2
HCFC1 [nucleoplasm]
(R-HSA-1592209)
K48polyUb,K63polyUb-HCFC1 [nucleoplasm]
(R-HSA-5690821)
0.802
7
UniProt:Q92685 ALG3
5
ALG3 [endoplasmic reticulum membrane]
(R-HSA-449287)
ALG3 W71R [endoplasmic reticulum membrane]
(R-HSA-4720466)
ALG3 G118D [endoplasmic reticulum membrane]
(R-HSA-4720468)
ALG3 M157K [endoplasmic reticulum membrane]
(R-HSA-4720484)
ALG3 R171Q [endoplasmic reticulum membrane]
(R-HSA-4720470)
0.729
4
UniProt:Q68CJ9 CREB3L3
10
CREB3L3(1-?) [nucleoplasm]
(R-HSA-6784629)
CREB3L3(1-?) [cytosol]
(R-HSA-6784654)
CREB3L3 [endoplasmic reticulum membrane]
(R-HSA-6784669)
CREB3L3(?-461) [endoplasmic reticulum membrane]
(R-HSA-6784710)
CREB3L3 [Golgi membrane]
(R-HSA-8874144)
CREB3L3(365-461) [Golgi membrane]
(R-HSA-8874130)
CREB3L3(1-364) [Golgi membrane]
(R-HSA-8874158)
CREB3L3(1-323) [cytosol]
(R-HSA-8874214)
CREB3L3(1-323) [nucleoplasm]
(R-HSA-8874217)
CREB3L3(324-364) [Golgi membrane]
(R-HSA-8874183)
0.623
3
UniProt:P35638 DDIT3
1
DDIT3 [nucleoplasm]
(R-HSA-381110)
0.623
2
UniProt:Q9NS37 ZHANG
0.623
3
UniProt:O43889 CREB3
7
CREB3(1-256) [nucleoplasm]
(R-HSA-8874190)
CREB3(1-256) [cytosol]
(R-HSA-8874135)
CREB3(1-291) [Golgi membrane]
(R-HSA-8874181)
CREB3(257-291) [Golgi membrane]
(R-HSA-8874207)
CREB3 [Golgi membrane]
(R-HSA-8874123)
CREB3(292-371) [Golgi membrane]
(R-HSA-8874173)
CREB3 [endoplasmic reticulum membrane]
(R-HSA-8874165)
0.592
2
UniProt:O00268 TAF4
1
TAF4 [nucleoplasm]
(R-HSA-65541)
0.558
2
UniProt:Q9NX47 MARH5
0.553
2
UniProt:Q96LL9 DJC30
0.553
2
UniProt:Q99675 CGRF1
0.553
2
UniProt:Q9NQQ7 S35C2
0.553
2
UniProt:Q14802 FXYD3
1
FXYD3 [plasma membrane]
(R-HSA-2752084)
0.553
2
UniProt:Q53HI1 UNC50
0.553
2
UniProt:Q9Y287 ITM2B
1
ITM2B(244-266) [extracellular region]
(R-HSA-976878)
0.553
2
UniProt:Q9BQA9 CYBC1
0.553
2
UniProt:Q9NW97 TMM51
0.553
2
UniProt:Q9Y3D6 FIS1
2
FIS1 [peroxisomal membrane]
(R-HSA-9033123)
FIS1 [cytosol]
(R-HSA-9033099)
0.553
2
UniProt:O95870 ABHGA
0.553
2
UniProt:Q9NV12 TM140
0.553
2
UniProt:Q9NZ43 USE1
1
USE1 [endoplasmic reticulum membrane]
(R-HSA-2193119)
0.553
2
UniProt:P02652 APOA2
6
APOA2(24-100) [cytosol]
(R-HSA-2395772)
APOA2(24-100) [early endosome]
(R-HSA-2569092)
APOA2(24-100) [endoplasmic reticulum lumen]
(R-HSA-174689)
APOA2(24-100) [extracellular region]
(R-HSA-174775)
p-APOA2 [endoplasmic reticulum lumen]
(R-HSA-8957014)
APOA2 [endoplasmic reticulum lumen]
(R-HSA-8956780)
0.553
2
UniProt:Q96CM8 ACSF2
1
ACSF2 [mitochondrial matrix]
(R-HSA-5696005)
0.553
2
UniProt:P43378 PTPN9
1
PTPN9 [nucleoplasm]
(R-HSA-9008907)
0.553
2
UniProt:Q9UNK0 STX8
0.553
2
UniProt:P48230 T4S4
0.553
2
UniProt:P05412 JUN
4
p-S63,S73-JUN [cytosol]
(R-HSA-8868682)
JUN [nucleoplasm]
(R-HSA-450250)
p-S63,S73-JUN [nucleoplasm]
(R-HSA-450237)
JUN [cytosol]
(R-HSA-168194)
0.524
4
UniProt:Q8TEY5 CREB3L4
7
CREB3L4(298-338) [Golgi membrane]
(R-HSA-8874221)
CREB3L4 [endoplasmic reticulum membrane]
(R-HSA-8874168)
CREB3L4 [Golgi membrane]
(R-HSA-8874128)
CREB3L4(1-338) [Golgi membrane]
(R-HSA-8874180)
CREB3L4(339-395) [Golgi membrane]
(R-HSA-8874140)
CREB3L4(1-297) [cytosol]
(R-HSA-8874188)
CREB3L4(1-297) [nucleoplasm]
(R-HSA-8874220)
0.483
2
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