Reactome | GGC-RAB2A [cytosol]

GGC-RAB2A [cytosol]

Stable Identifier

R-HSA-8873963

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ras-related protein Rab-2A, RAB2A_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P61019 RAB2A

Gene Names

RAB2A, RAB2

Chain

initiator methionine:, chain:2-212

Reference Genes

BioGPS Gene:5862 RAB2A

COSMIC (genes):RAB2A RAB2A

CTD Gene:5862 RAB2A

dbSNP Gene:5862 RAB2A

ENSEMBL:ENSG00000104388 RAB2A

ENSEMBL_homo_sapiens_GENE:ENSG00000104388.15 RAB2A

HGNC:9763 RAB2A

KEGG Gene (Homo sapiens):5862 RAB2A

Monarch:5862 RAB2A

NCBI Gene:5862 RAB2A

OMIM:179509 RAB2A

UCSC:P61019 RAB2A

Reference Transcript

Other Identifiers

11750002_a_at

11758857_at

11758858_s_at

11758859_at

17069250

208730_PM_x_at

208730_x_at

208731_PM_at

208731_at

208732_PM_at

208732_at

208733_PM_at

208733_at

208734_PM_x_at

208734_x_at

3100172

3100173

3100174

3100189

3100198

3100203

3100204

3100205

3100209

3100222

3100228

3100229

3100230

3100231

3100232

3100233

3100234

3100235

32581_at

5862

623_s_at

8146564

A_14_P117424

A_14_P201746

A_23_P253949

A_23_P340251

A_24_P102080

GE543964

GE56685

GE86646

GO:0000139

GO:0000166

GO:0001669

GO:0003824

GO:0003924

GO:0005515

GO:0005525

GO:0005576

GO:0005615

GO:0005634

GO:0005764

GO:0005765

GO:0005773

GO:0005783

GO:0005789

GO:0005794

GO:0005829

GO:0006888

GO:0007030

GO:0015031

GO:0016020

GO:0016192

GO:0016787

GO:0019003

GO:0031410

GO:0033116

GO:0042470

GO:0043226

GO:0070062

HMNXSV003016033

Hs.78305.0.A1_3p_at

Hs.78305.0.A3_3p_at

Hs.78305.0.A4_3p_at

Hs.78305.0.A5_3p_at

ILMN_1652394

ILMN_1891857

M28213_s_at

PH_hs_0004517

PH_hs_0038533

TC08000410.hg

X12953_at

g550061_3p_a_at

Participates

as a member of

GGC-RABs [cytosol] (Homo sapiens)

Other forms of this molecule

RAB2A [cytosol]

RAB2A [Golgi membrane]

Inferred To

unc-108 [cytosol] (Caenorhabditis elegans)

RAB2A [cytosol] (Bos taurus)

RAB2A [cytosol] (Sus scrofa)

rab2a [cytosol] (Danio rerio)

rab2a [cytosol] (Xenopus tropicalis)

GGC-RAB2A [cytosol] (Canis familiaris)

GGC-RAB2A [cytosol] (Dictyostelium discoideum)

GGC-RAB2A [cytosol] (Drosophila melanogaster)

GGC-RAB2A [cytosol] (Gallus gallus)

GGC-RAB2A [cytosol] (Mus musculus)

GGC-RAB2A [cytosol] (Plasmodium falciparum)

GGC-RAB2A [cytosol] (Rattus norvegicus)

Modified Residues

Name

S-geranylgeranyl-L-cysteine at 211

Coordinate

211

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Name

S-geranylgeranyl-L-cysteine at 212

Coordinate

212

PsiMod Name

S-geranylgeranyl-L-cysteine [MOD:00113]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.

Cross References

RefSeq

NP_002856.1, NP_001229573.1

OpenTargets

ENSG00000104388

HPA

ENSG00000104388-RAB2A

GeneCards

P61019

Ensembl

ENSG00000104388, ENSP00000431846, ENSP00000262646, ENST00000531289, ENST00000262646

PRO

P61019

Pharos - Targets

P61019

PDB

1Z0A

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.831	8
UniProt:Q96FJ0 STAMBPL1	1	STAMBPL1 [cytosol] (R-HSA-6783264)	0.781	10
UniProt:Q3MII6 TBC1D25	1	TBC1D25 [autophagosome] (R-HSA-8854607)	0.556	3
UniProt:P51149 RAB7A	7	RAB7A [secretory granule membrane] (R-HSA-6804969) RAB7A [plasma membrane] (R-HSA-6804990) RAB7A [cytosol] (R-HSA-8870415) RAB7A [phagocytic vesicle membrane] (R-HSA-9636586) RAB7A [lysosomal membrane] (R-HSA-2213231) GGC-RAB7A [cytosol] (R-HSA-8870438) GGC-RAB7A [lysosomal membrane] (R-HSA-8877454)	0.527	2
UniProt:P10636-8 MAPT	3	p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) MAPT-8 [cytosol] (R-HSA-9619519)	0.527	4
UniProt:Q16581 C3AR1	3	C3AR1 [plasma membrane] (R-HSA-444727) C3AR1 [azurophil granule membrane] (R-HSA-6799517) C3AR1 [specific granule membrane] (R-HSA-6799516)	0.527	2
UniProt:P21796 VDAC1	7	PolyUb-VDAC1 [mitochondrial outer membrane] (R-HSA-6783079) VDAC1 [mitochondrial intermembrane space] (R-HSA-1267960) VDAC1 [mitochondrial outer membrane] (R-HSA-1267988) Ub-VDAC1 [mitochondrial outer membrane] (R-HSA-9834989) K48polyUb-VDAC1 [mitochondrial outer membrane] (R-HSA-5205624) K63polyUb-VDAC1 [mitochondrial outer membrane] (R-HSA-9834037) p-S65-Ub:VDAC1 [mitochondrial outer membrane] (R-HSA-9834991)	0.527	2

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