Casein kinase II phosphorylates STARD10

Stable Identifier
R-HSA-8873929
Type
Reaction [transition]
Species
Homo sapiens
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PCTP-like protein (STARD10) is a member of the steroidogenic acute regulatory (StAR) protein-related lipid transfer (START) domain proteins that are implicated in lipid transport, metabolism, and signaling. STARD10 is thought to function as a dual specificity lipid transfer protein capable of shuttling phosphatidylcholine and phosphatidylethanolamine between membranes. Its lipid transfer activity is negatively regulated by casein kinase, a serine/threonine-protein kinase which phosphorylates STARD10 on a serine residue at position 284 (Olayioye et al. 2007).

Literature References
PubMed ID Title Journal Year
17561512 Phosphorylation of StarD10 on serine 284 by casein kinase II modulates its lipid transfer activity

Olayioye, MA, Buchholz, M, Schmid, S, Schoffler, P, Hoffmann, P, Pomorski, T

J. Biol. Chem. 2007
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Catalyst Activity

protein serine/threonine kinase activity of Casein kinase II [cytosol]

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