Casein kinase II phosphorylates STARD10

Stable Identifier
R-HSA-8873929
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Casein kinase II phosphorylates STARD10
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PCTP-like protein (STARD10) is a member of the steroidogenic acute regulatory (StAR) protein-related lipid transfer (START) domain proteins that are implicated in lipid transport, metabolism, and signaling. STARD10 is thought to function as a dual specificity lipid transfer protein capable of shuttling phosphatidylcholine and phosphatidylethanolamine between membranes. Its lipid transfer activity is negatively regulated by casein kinase, a serine/threonine-protein kinase which phosphorylates STARD10 on a serine residue at position 284 (Olayioye et al. 2007).
Literature References
PubMed ID Title Journal Year
17561512 Phosphorylation of StarD10 on serine 284 by casein kinase II modulates its lipid transfer activity

Schoffler, P, Buchholz, M, Pomorski, T, Hoffmann, P, Schmid, S, Olayioye, MA

J. Biol. Chem. 2007
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Catalyst Activity

protein serine/threonine kinase activity of Casein kinase II [cytosol]

Physical Entity
Casein kinase II [cytosol] (Homo sapiens)
Activity
protein serine/threonine kinase activity (GO:0004674)
Orthologous Events
Casein kinase II phosphorylates STARD10 (Bos taurus)
Casein kinase II phosphorylates STARD10 (Caenorhabditis elegans)
Casein kinase II phosphorylates STARD10 (Canis familiaris)
Casein kinase II phosphorylates STARD10 (Mus musculus)
Casein kinase II phosphorylates STARD10 (Rattus norvegicus)
Casein kinase II phosphorylates STARD10 (Sus scrofa)
Authored
Jassal, B  (2016-05-20)
Reviewed
D'Eustachio, P  (2016-07-15)
Created
Jassal, B  (2016-05-20)
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