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ARHGEF26 [cytosol]
Stable Identifier
R-HSA-8873912
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Rho guanine nucleotide exchange factor 26, ARHGQ_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRAGE signals death through JNK (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
ARHGEF26 [cytosol] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
GEFs activate RhoA,B,C (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
ARHGEF26 [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GEFs activate CDC42 (Homo sapiens)
CDC42 GEFs [cytosol] (Homo sapiens)
ARHGEF26 [cytosol] (Homo sapiens)
RHOG GTPase cycle (Homo sapiens)
RHOG GEFs activate RHOG (Homo sapiens)
RHOG GEFs [cytosol] (Homo sapiens)
ARHGEF26 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96DR7 ARHGEF26
Gene Names
ARHGEF26, SGEF, HMFN1864
Chain
chain:1-871
Reference Genes
BioGPS Gene:26084 ARHGEF26
COSMIC (genes):ARHGEF26 ARHGEF26
CTD Gene:26084 ARHGEF26
dbSNP Gene:26084 ARHGEF26
ENSEMBL:ENSG00000114790 ARHGEF26
ENSEMBL_homo_sapiens_GENE:ENSG00000114790.13 ARHGEF26
ENSEMBL_homo_sapiens_GENE:ENSG00000277101.4 ARHGEF26
HGNC:24490 ARHGEF26
KEGG Gene (Homo sapiens):26084 ARHGEF26
Monarch:26084 ARHGEF26
NCBI Gene:26084 ARHGEF26
OMIM:617552 ARHGEF26
UCSC:Q96DR7 ARHGEF26
Reference Transcript
RefSeq:NM_001251962.1 ARHGEF26
RefSeq:NM_015595.3 ARHGEF26
RefSeq:NM_001251963.1 ARHGEF26
Other Identifiers
11734164_a_at
11734165_x_at
11746140_a_at
11746141_x_at
11746981_x_at
16947148
222121_PM_at
222121_at
227197_PM_at
227197_at
233903_3p_s_at
233903_PM_s_at
233903_s_at
26084
2648536
2648537
2648538
2648539
2648540
2648542
2648547
2648548
2648552
2648553
2648554
2648555
2648558
2648561
2648564
2648565
2648567
2648571
2648572
2648573
2648575
2648576
2648577
2648578
2648579
2648581
57673_at
58281_r_at
8083471
A_14_P136564
A_23_P69100
A_32_P5276
GE82021
GO:0001726
GO:0001886
GO:0005085
GO:0005515
GO:0005829
GO:0030154
GO:0042995
GO:0048856
GO:0097178
GO:0098772
HMNXSV003020536
Hs.12891.0.A1_3p_at
Hs.240845.0.S1_3p_a_at
Hs.240845.1.S1_3p_at
ILMN_1773042
PH_hs_0012928
TC03000844.hg
Participates
as a candidate of
CDC42 GEFs [cytosol] (Homo sapiens)
RHOG GEFs [cytosol] (Homo sapiens)
as a member of
GEFs [cytosol] (Homo sapiens)
Inferred To
Exn [cytosol]
(Drosophila melanogaster)
Arhgef26 [cytosol]
(Mus musculus)
Arhgef26 [cytosol]
(Rattus norvegicus)
ephx-1 [cytosol]
(Caenorhabditis elegans)
ARHGEF26 [cytosol]
(Bos taurus)
ARHGEF26 [cytosol]
(Canis familiaris)
ARHGEF26 [cytosol]
(Gallus gallus)
ARHGEF26 [cytosol]
(Sus scrofa)
arhgef26 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_056410.3
,
NP_001238892.1
,
NP_001238891.1
OpenTargets
ENSG00000114790
HPA
ENSG00000114790-ARHGEF26
GeneCards
Q96DR7
Ensembl
ENSP00000487265
,
ENST00000629129
,
ENST00000465817
,
ENSP00000423418
,
ENSG00000114790
,
ENSP00000486665
,
ENST00000630729
,
ENSP00000484367
,
ENST00000618535
,
ENST00000614308
,
ENSP00000481927
,
ENST00000496710
,
ENST00000356448
,
ENSP00000424446
,
ENSP00000348828
,
ENST00000465093
,
ENSP00000423295
,
ENSG00000277101
PRO
Q96DR7
Pharos - Targets
Q96DR7
PDB
7YKG
,
6MYE
HMDB Protein
HMDBP08578
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O14936 CASK
1
CASK [cytosol]
(R-HSA-373631)
0.527
2
UniProt:P46199 MTIF2
1
MTIF2 [mitochondrial matrix]
(R-HSA-5368271)
0.527
2
UniProt:P31327 CPS1
1
CPS1 [mitochondrial matrix]
(R-HSA-70544)
0.527
3
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