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ARHGEF35 [cytosol]
Stable Identifier
R-HSA-8871615
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Rho guanine nucleotide exchange factor 35, ARG35_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRAGE signals death through JNK (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
ARHGEF35 [cytosol] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
GEFs activate RhoA,B,C (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
ARHGEF35 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:A5YM69 ARHGEF35
Gene Names
ARHGEF35, ARHGEF5L
Chain
chain:1-484
Reference Genes
BioGPS Gene:445328 ARHGEF35
COSMIC (genes):ARHGEF35 ARHGEF35
CTD Gene:445328 ARHGEF35
dbSNP Gene:445328 ARHGEF35
ENSEMBL:ENSG00000213214 ARHGEF35
HGNC:33846 ARHGEF35
KEGG:hsa:445328 ARHGEF35
Monarch:445328 ARHGEF35
NCBI Gene:445328 ARHGEF35
UCSC:A5YM69 ARHGEF35
Reference Transcript
RefSeq:NM_001003702.3 ARHGEF35
RefSeq:NM_001368318.1 ARHGEF35
RefSeq:XM_017030457.1 ARHGEF35
Other Identifiers
11736628_s_at
17063996
244386_PM_at
244386_at
2925942
2925944
3029630
3029631
3029633
3029635
3029636
3029650
3029658
3029659
3077438
3077567
3077569
3077570
3077572
3077574
3077575
3077576
3077577
3077578
3077585
3077586
3077622
3077623
3077629
445328
77297_at
8143610
A_24_P701776
HMNXSV003050531
Hs.187686.0.A1_3p_at
Hs.187686.0.A1_3p_x_at
PH_hs_0038308
TC07003305.hg
Participates
as a candidate of
GEFs [cytosol] (Homo sapiens)
Cross References
RefSeq
XP_016885946.1
,
NP_001355247.1
,
NP_001003702.2
ENSEMBL
ENSP00000510684
,
ENST00000378115
,
ENSP00000367355
,
ENSG00000213214
,
ENST00000688754
OpenTargets
ENSG00000213214
GeneCards
ARHGEF35
HPA
ENSG00000213214-ARHGEF35
PRO
A5YM69
Pharos - Targets
A5YM69
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.527
3
UniProt:P13716 ALAD
4
ALAD [ficolin-1-rich granule lumen]
(R-HSA-6801397)
ALAD [extracellular region]
(R-HSA-6806504)
ALAD [secretory granule lumen]
(R-HSA-6801404)
ALAD [cytosol]
(R-HSA-189453)
0.527
2
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