TFPA2A homodimer and NPM1 bind the HSPD1 gene promoter

Stable Identifier
R-HSA-8869542
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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TFPA2A homodimer and NPM1 bind the HSPD1 gene promoter
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In response to retinoic acid treatment, TFAP2A (AP-2 alpha) homodimers in complex with NPM1 (nucleophosmin) are recruited to the AP-2 alpha response element in the promoter of the mitochondrial chaperonin gene HSPD1 (Hsp60) (Liu et al. 2007).

Literature References
PubMed ID Title Journal Year
17318229 Nucleophosmin acts as a novel AP2alpha-binding transcriptional corepressor during cell differentiation

Liu, H, Tan, BC, Tseng, KH, Chuang, CP, Yeh, CW, Chen, KD, Lee, SC, Yung, BY

EMBO Rep. 2007
Participants
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Output
Participant Of
hasEvent
Authored
Orlic-Milacic, M  (2016-03-14)
Reviewed
Zarelli, VE  (2016-05-04)
Dawid, IB  (2016-05-04)
Created
Orlic-Milacic, M  (2016-05-05)
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