In response to retinoic acid treatment, TFAP2A (AP-2 alpha) homodimers in complex with NPM1 (nucleophosmin) are recruited to the AP-2 alpha response element in the promoter of the mitochondrial chaperonin gene HSPD1 (Hsp60) (Liu et al. 2007).
Liu, H, Tan, BC, Tseng, KH, Chuang, CP, Yeh, CW, Chen, KD, Lee, SC, Yung, BY
© 2021 Reactome