TFPA2A homodimer and NPM1 bind the HSPD1 gene promoter

Stable Identifier
R-HSA-8869542
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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TFPA2A homodimer and NPM1 bind the HSPD1 gene promoter
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In response to retinoic acid treatment, TFAP2A (AP-2 alpha) homodimers in complex with NPM1 (nucleophosmin) are recruited to the AP-2 alpha response element in the promoter of the mitochondrial chaperonin gene HSPD1 (Hsp60) (Liu et al. 2007).

Literature References
PubMed ID Title Journal Year
17318229 Nucleophosmin acts as a novel AP2alpha-binding transcriptional corepressor during cell differentiation

Liu, H, Tan, BC, Tseng, KH, Chuang, CP, Yeh, CW, Chen, KD, Lee, SC, Yung, BY

EMBO Rep. 2007
Participants
Input
Output
Participant Of
hasEvent
Authored
Orlic-Milacic, M  (2016-03-14)
Reviewed
Zarelli, VE  (2016-05-04)
Dawid, IB  (2016-05-04)
Created
Orlic-Milacic, M  (2016-05-05)