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KIAA0319 [clathrin-coated endocytic vesicle membrane]
Stable Identifier
R-HSA-8869092
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
clathrin-coated endocytic vesicle membrane
Synonyms
Dyslexia-associated protein KIAA0319, K0319_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Clathrin-mediated endocytosis (Homo sapiens)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin recruits auxilins to the clathrin-coated vesicle (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Dissociation of clathrin-associated proteins (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
RAB5 and GAPVD1 bind AP-2 (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
KIAA0319 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5VV43 KIAA0319
Gene Names
KIAA0319
Chain
signal peptide:1-20, chain:21-1072
Reference Genes
BioGPS Gene:9856 KIAA0319
COSMIC (genes):KIAA0319 KIAA0319
CTD Gene:9856 KIAA0319
dbSNP Gene:9856 KIAA0319
ENSEMBL:ENSG00000137261 KIAA0319
HGNC:21580 KIAA0319
Monarch:9856 KIAA0319
NCBI Gene:9856 KIAA0319
OMIM:609269 KIAA0319
UCSC:Q5VV43 KIAA0319
Reference Transcript
RefSeq:XM_011515026.2 KIAA0319
RefSeq:NM_001168375.1 KIAA0319
RefSeq:XM_011515025.2 KIAA0319
RefSeq:NM_001168376.1 KIAA0319
RefSeq:XM_017011545.1 KIAA0319
RefSeq:NM_014809.3 KIAA0319
RefSeq:XM_017011541.1 KIAA0319
RefSeq:NM_001168377.1 KIAA0319
RefSeq:NM_001168374.1 KIAA0319
Other Identifiers
11740304_a_at
11740305_at
11740306_a_at
17016160
206017_PM_at
206017_at
2945599
2945600
2945601
2945602
2945603
2945604
2945606
2945607
2945609
2945610
2945611
2945612
2945614
2945615
2945616
2945617
2945618
2945619
2945620
2945622
2945624
2945625
2945626
2945627
2945628
2945629
2945632
2945633
2945634
2945639
2945640
2945642
2945644
39589_at
8124240
9856
A_23_P168324
A_24_P166397
GE53053
GO:0001764
GO:0005515
GO:0005768
GO:0005769
GO:0005886
GO:0007399
GO:0010996
GO:0016020
GO:0030517
GO:0030669
GO:0031410
GO:0031901
GO:0033555
GO:0043226
GO:0043231
GO:0048692
GO:0048856
GO:0048870
GO:0060391
GO:2000171
HMNXSV003009505
HMNXSV003056746
ILMN_1657497
PH_hs_0002330
TC06001326.hg
g7662053_3p_at
Participates
as a component of
KIAA0319 dimer [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Other forms of this molecule
KIAA0319 [plasma membrane]
Inferred To
KIAA0319 [clathrin-coated endocytic vesicle membrane]
(Bos taurus)
KIAA0319 [clathrin-coated endocytic vesicle membrane]
(Canis familiaris)
KIAA0319 [clathrin-coated endocytic vesicle membrane]
(Gallus gallus)
KIAA0319 [clathrin-coated endocytic vesicle membrane]
(Rattus norvegicus)
KIAA0319 [clathrin-coated endocytic vesicle membrane]
(Sus scrofa)
Kiaa0319 [clathrin-coated endocytic vesicle membrane]
(Mus musculus)
Dmel\CG7565 [clathrin-coated endocytic vesicle membrane]
(Drosophila melanogaster)
Cross References
ENSEMBL
ENSP00000439700
,
ENSP00000367459
,
ENST00000535378
,
ENST00000537886
,
ENST00000378214
,
ENSP00000401086
,
ENSP00000442403
,
ENST00000430948
OpenTargets
ENSG00000137261
HPA
ENSG00000137261-KIAA0319
PRO
Q5VV43
Pharos - Targets
Q5VV43
GlyGen
Q5VV43
PDB
2E7M
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