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MAGOH,MAGOHB [nucleoplasm]
Stable Identifier
R-HSA-8868752
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
Signaling by ROBO receptors (Homo sapiens)
Regulation of expression of SLITs and ROBOs (Homo sapiens)
Translation of ROBO3.2 mRNA initiates NMD (Homo sapiens)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Homo sapiens)
Core Exon Junction Complex (Core EJC) [cytosol] (Homo sapiens)
Magoh-Y14 complex [cytosol] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Translated ROBO3.2 mRNA in complex with NMD-initiating UPF2 [cytosol] (Homo sapiens)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Homo sapiens)
Core Exon Junction Complex (Core EJC) [cytosol] (Homo sapiens)
Magoh-Y14 complex [cytosol] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Translation of ROBO3.2 mRNA is negatively regulated by NMD (Homo sapiens)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Homo sapiens)
Core Exon Junction Complex (Core EJC) [cytosol] (Homo sapiens)
Magoh-Y14 complex [cytosol] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Translated ROBO3.2 mRNA in complex with NMD-initiating UPF2 [cytosol] (Homo sapiens)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Homo sapiens)
Core Exon Junction Complex (Core EJC) [cytosol] (Homo sapiens)
Magoh-Y14 complex [cytosol] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
RNA Polymerase II Transcription Termination (Homo sapiens)
Cleavage of mRNA at the 3'-end (Homo sapiens)
3' end cleaved, ligated exon containing complex [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
Nonsense-Mediated Decay (NMD) (Homo sapiens)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Homo sapiens)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Homo sapiens)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Homo sapiens)
Core Exon Junction Complex (Core EJC) [cytosol] (Homo sapiens)
Magoh-Y14 complex [cytosol] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Homo sapiens)
Core Exon Junction Complex (Core EJC) [cytosol] (Homo sapiens)
Magoh-Y14 complex [cytosol] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
SMG6 hydrolyzes mRNA with premature termination codon (Homo sapiens)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Homo sapiens)
Core Exon Junction Complex (Core EJC) [cytosol] (Homo sapiens)
Magoh-Y14 complex [cytosol] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Homo sapiens)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Homo sapiens)
Core Exon Junction Complex (Core EJC) [cytosol] (Homo sapiens)
Magoh-Y14 complex [cytosol] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Homo sapiens)
Core Exon Junction Complex (Core EJC) [cytosol] (Homo sapiens)
Magoh-Y14 complex [cytosol] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Homo sapiens)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Homo sapiens)
Core Exon Junction Complex (Core EJC) [cytosol] (Homo sapiens)
Magoh-Y14 complex [cytosol] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Homo sapiens)
Exon Junction:UPF2:UPF3 Complex [cytosol] (Homo sapiens)
Core Exon Junction Complex (Core EJC) [cytosol] (Homo sapiens)
Magoh-Y14 complex [cytosol] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
Transport of Mature Transcript to Cytoplasm (Homo sapiens)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Homo sapiens)
Docking of the TAP:EJC Complex with the NPC (Homo sapiens)
NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Homo sapiens)
capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Homo sapiens)
NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Homo sapiens)
capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Transport of the export-competent mRNP complex through the NPC (Homo sapiens)
NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Homo sapiens)
EJC [cytosol] (Homo sapiens)
Core Exon Junction Complex (Core EJC) [cytosol] (Homo sapiens)
Magoh-Y14 complex [cytosol] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
mRNP complex dissociates from cytosolic face of NPC (Homo sapiens)
NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Homo sapiens)
EJC [cytosol] (Homo sapiens)
Core Exon Junction Complex (Core EJC) [cytosol] (Homo sapiens)
Magoh-Y14 complex [cytosol] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
mRNA:CBC:EJC:POLDIP3 [cytosol] (Homo sapiens)
EJC [cytosol] (Homo sapiens)
Core Exon Junction Complex (Core EJC) [cytosol] (Homo sapiens)
Magoh-Y14 complex [cytosol] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
mRNA 3'-end processing (Homo sapiens)
Cleavage of mRNA at the 3'-end (Homo sapiens)
3' end cleaved, ligated exon containing complex [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally (Homo sapiens)
Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Spliced mRNP [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
mRNA polyadenylation (Homo sapiens)
3' end cleaved, ligated exon containing complex [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Formation of the Spliceosomal B* complex (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Spliceosomal B* complex [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal C* complex (Homo sapiens)
Spliceosomal C complex [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal P complex and exon ligation (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Homo sapiens)
EJC [nucleoplasm] (Homo sapiens)
Core EJC [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
MAGOH,MAGOHB [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
23917022
Two mammalian MAGOH genes contribute to exon junction complex composition and nonsense-mediated decay
Gehring, NH
,
Kulozik, AE
,
Wachsmuth, L
,
Singh, KK
RNA Biol
2013
Participants
members
MAGOH [nucleoplasm]
(Homo sapiens)
MAGOHB [nucleoplasm]
(Homo sapiens)
Participates
as a component of
Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
Magoh-Y14 complex [cytosol] (Homo sapiens)
Inferred To
Ghost homologue of MAGOH,MAGOHB [nucleoplasm]
(Saccharomyces cerevisiae)
Ghost homologue of MAGOH,MAGOHB [nucleoplasm]
(Xenopus tropicalis)
MAGOHB [nucleoplasm]
(Gallus gallus)
Magoh [nucleoplasm]
(Mus musculus)
mag-1 [nucleoplasm]
(Caenorhabditis elegans)
mago [nucleoplasm]
(Drosophila melanogaster)
mnh1 [nucleoplasm]
(Schizosaccharomyces pombe)
MAGOH,MAGOHB [nucleoplasm]
(Bos taurus)
MAGOH,MAGOHB [nucleoplasm]
(Canis familiaris)
MAGOH,MAGOHB [nucleoplasm]
(Plasmodium falciparum)
MAGOH,MAGOHB [nucleoplasm]
(Rattus norvegicus)
MAGOH,MAGOHB [nucleoplasm]
(Sus scrofa)
magoh [nucleoplasm]
(Danio rerio)
magoh [nucleoplasm]
(Dictyostelium discoideum)
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